Browsing Faculty of Arts and Sciences by Title
Now showing items 2894-2913 of 24465
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Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
(Springer Science and Business Media LLC, 2019-05-20)Base editing requires that the target sequence satisfy the protospacer adjacent motif requirement of the Cas9 domain and that the target nucleotide be located within the editing window of the base editor. To increase the ... -
Circulating C3 is Necessary and Sufficient for Induction of Autoantibody-Mediated Arthritis in a Mouse Model
(John Wiley & Sons, 2007)Objective. For the inflammation characteristic of rheumatoid arthritis, the relative contribution of mediators produced locally in the synovium versus those circulating systemically is unknown. Complement factor C3 is made ... -
Circulation in the Eastern Levantine Basin Determined by Inverse Methods
(American Meteorological Society, 1988)A finite difference linear inverse model is applied to hydrographic data from six summer and fall cruises in a small area (250 × 200 km) of the eastern Mediterranean sea. The temperature and salinity equations are used to ... -
Circus Aesthetics, Travel, History, and Mourning in the Poetry of Robert Hayden
(2016-02-16)Circus Aesthetics examines the work of the African American poet Robert Hayden and engages with the problem of identifying different frameworks with which to think about Hayden’s poetry and African American literature more ... -
Cis-regulatory sequence variation and association with Mycoplasma load in natural populations of the house finch (Carpodacus mexicanus)
(Blackwell Publishing Ltd, 2013)Characterization of the genetic basis of fitness traits in natural populations is important for understanding how organisms adapt to the changing environment and to novel events, such as epizootics. However, candidate ... -
Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity
(Society for Neuroscience, 2016)The neocortex contains hundreds to thousands of distinct subtypes of precisely connected neurons, allowing it to perform remarkably complex tasks of high-level cognition. Callosal projection neurons (CPN) connect the ... -
Cities of Amber: Antigrowth Politics and the Making of Modern Liberalism
(2023-11-21)The skyrocketing cost of living in cities from New York to San Francisco is an issue of enormous consequence in American life today. Yet its historical causes, until now, were not well understood. This dissertation is the ... -
Citizen Contention and Campus Calm: The Paradox of Chinese Civil Society
(Events Pub. Co, 2014)Contrary to conventional predictions, the growth of protest and civil society in contemporary China seems more conducive to the resilience of authoritarianism than to imminent democratization. -
Citizen Science as a New Tool in Dog Cognition Research
(Public Library of Science, 2015)Family dogs and dog owners offer a potentially powerful way to conduct citizen science to answer questions about animal behavior that are difficult to answer with more conventional approaches. Here we evaluate the quality ... -
Citizens of the Chemical Complex: Industrial Expertise and Science Philanthropy in Imperial and Weimar Germany
(2014-02-25)This dissertation is a social and cultural history of chemical industrialists and their role in the development of both science and capitalism in the nineteenth and twentieth centuries. It focuses on the case of Germany, ... -
Citizens of the Market: New Forms of International Migration and their Consequences for People, Parties and Political Systems
(2014-02-25)How does high-mobility migration affect politics in the migrants' countries of origin? This dissertation examines the socio-political effects of intra-EU migrations using quantitative and qualitative data from Romania and ... -
Citizenship; Freedom; Status
(University of Chicago Press, 1991) -
City Services for a Smarter Boston: Constituent Driven Intelligence through BOS:311
(2022-06-03)This thesis is an interdisciplinary study of BOS:311, the non-emergency city services program for the City of Boston. The study situates BOS:311 within the context of the Smart City, a budding object of scholarly inquiry ... -
A City within a City: Community Development and the Struggle over Harlem, 1961-2001
(2013-07-05)This dissertation examines the idea of community development in the last four decades of the twentieth century through the example of the Harlem neighborhood of New York City and, in doing so, explains the broader ... -
CitySense: A Vision for an Urban-Scale Wireless Networking Testbed
(2007)In this paper, we present the vision for an open, urban-scale wireless networking testbed, called CitySense, with the goal of supporting the development and evaluation of novel wireless systems that span an entire city. ... -
Civic Knighthood in the Early Renaissance: Leonardo Bruni's De militia (ca. 1420)
(2011-12-20)Leonardo Bruni's aim in the De militia (ca. 1420) was to co-opt the most glamorous of medieval ideals, the ideal of chivalry, and to reinterpret it in terms of Greco-Roman ideals of military service. In so doing he aimed ... -
Civil Rights in International Law: Compliance with Aspects of the "International Bill of Rights"
(Indiana University Press, 2009)International law has developed what many might consider a constitutional understanding of individual civil rights that individuals can claim vis-a-vis their own governments. This paper discusses the development of aspects ... -
Civil Rights Law at Work: Sex Discrimination and the Rise of Maternity Leave Policies
(University of Chicago Press, 1999)By the time Congress passed the Family and Medical Leave Act of 1993, many employers had created maternity leave programs. Analysts argue that they did so in response to the feminization of the workforce. This study charts ... -
Civil Society and the State: The Interplay between Cooperation and Minimum Wage Regulation
(2009)In a cross-section of countries, state regulation of labor markets is strongly negatively correlated with the quality of labor relations. In this paper, we argue that these facts reflect different ways to regulate labor ... -
Civil Society Reconsidered: The Durable Nature and Community Structure of Collective Civic Action
(University of Chicago Press, 2005)This article develops a conceptual framework on civil society that shifts the dominant focus on individuals to collective action events— civic and protest alike—that bring people together in public to realize a common ...