Browsing Faculty of Arts and Sciences by Title

Now showing items 3004-3023 of 24540

    • Clogging Mechanisms in Converging Microchannels 

      Massenburg, Sorell S. (2016-01-29)
      Many technological and biomedical applications ranging from water filtration and oil extraction to arteriosclerosis and vein thrombosis rely upon the transport of solids in liquids. Particulate matter suspended in liquid ...

    • Clonal analyses and gene profiling identify genetic biomarkers of human brown and white preadipocyte thermogenic potential 

      Xue, Ruidan; Lynes, Matthew D.; Dreyfuss, Jonathan M.; Shamsi, Farnaz; Schulz, Tim J.; Zhang, Hongbin; Huang, Tian Lian; Townsend, Kristy L.; Li, Yiming; Takahashi, Hirokazu; Weiner, Lauren S.; White, Andrew P.; Lynes, Maureen S.; Rubin, Lee L.; Goodyear, Laurie J.; Cypess, Aaron M.; Tseng, Yu-Hua (2015)
      Targeting brown adipose tissue (BAT) content or activity has therapeutic potential for treating obesity and the metabolic syndrome by increasing energy expenditure. Both inter- and intra-individual differences contribute ...

    • Clonal Analysis of Mucosal SIV-Specific CD8+ T Cell Responses 

      Sircar, Piya (2013-02-26)
      CD8+ T cells responses are critical in the immune defense against human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection. A major challenge for vaccine development is that HIV/SIV can rapidly ...

    • Clonal analysis of native and malignant hematopoiesis using color barcoding in zebrafish 

      Henninger, Jonathan (2018-01-19)
      Hematopoietic stem cells (HSCs) emerge from the dorsal aorta during embryogenesis and sustain lifelong blood production. Over time, HSC clones accumulate mutations that may cause clonal expansion at the expense of normal ...

    • Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition 

      Burger, Jan A.; Landau, Dan A.; Taylor-Weiner, Amaro; Bozic, Ivana; Zhang, Huidan; Sarosiek, Kristopher; Wang, Lili; Stewart, Chip; Fan, Jean; Hoellenriegel, Julia; Sivina, Mariela; Dubuc, Adrian M.; Fraser, Cameron; Han, Yulong; Li, Shuqiang; Livak, Kenneth J.; Zou, Lihua; Wan, Youzhong; Konoplev, Sergej; Sougnez, Carrie; Brown, Jennifer R.; Abruzzo, Lynne V.; Carter, Scott L.; Keating, Michael J.; Davids, Matthew S.; Wierda, William G.; Cibulskis, Kristian; Zenz, Thorsten; Werner, Lillian; Cin, Paola Dal; Kharchencko, Peter; Neuberg, Donna; Kantarjian, Hagop; Lander, Eric; Gabriel, Stacey; O'Brien, Susan; Letai, Anthony; Weitz, David A.; Nowak, Martin A.; Getz, Gad; Wu, Catherine J. (Nature Publishing Group, 2016)
      Resistance to the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has been attributed solely to mutations in BTK and related pathway molecules. Using whole-exome and deep-targeted sequencing, we dissect evolution of ...

    • Cloning and Sequencing of a Form II Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase from the Bacterial Symbiont of the Hydrothermal Vent Tubeworm Riftia pachyptila 

      Robinson, Jonathan J; Stein, Jeffrey L; Cavanaugh, Colleen Marie (American Society for Microbiology, 1998)
      The bacterial symbiont of the hydrothermal vent tubeworm fixes carbon via the Calvin-Benson cycle and has been shown previously to express a form II ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO). The gene cbbM, ...

    • Cloning, Characterisation and Comparative Analysis of a Starch Synthase IV Gene in Wheat: Functional and Evolutionary Implications 

      Leterrier, Marina; Holappa, Lynn D; Broglie, Karen E; Beckles, Diane M (BioMed Central, 2008)
      Background: Starch is of great importance to humans as a food and biomaterial, and the amount and structure of starch made in plants is determined in part by starch synthase (SS) activity. Five SS isoforms, SSI, II, III, ...

    • A close call: does the location of incision at cesarean delivery matter in patients with vasa previa? A case report. 

      Neuhausser, Werner M; Baxi, Laxmi V (F1000Research, 2013)
      We present here a case of vasa previa in a multipara, diagnosed at the time of her late second trimester ultrasonogram. The patient subsequently underwent an elective cesarean section after 37 weeks gestation, giving birth ...

    • Closed String Tachyon Condensation at c =1 

      Karczmarek, Joanna L.; Strominger, Andrew (Springer Verlag, 2004)
      The c=1 matrix model, with or without a type 0 hat, has an exact quantum solution corresponding to closed string tachyon condensation along a null surface. The condensation occurs, and spacetime dissolves, at a finite ...

    • Closely overlapping responses to tools and hands in left lateral occipitotemporal cortex 

      Bracci, S.; Cavina-Pratesi, C.; Ietswaart, M.; Caramazza, Alfonso; Peelen, M. V. (American Physiological Society, 2011)
      The perception of object-directed actions performed by either hands or tools recruits regions in left fronto-parietal cortex. Here, using functional MRI (fMRI), we tested whether the common role of hands and tools in object ...

    • Closely related bird species demonstrate flexibility between beak morphology and underlying developmental programs 

      Mallarino, Ricardo; Campas, O.; Fritz, Joerg; Burns, K. J.; Weeks, Olivia Grace; Brenner, Michael P.; Abzhanov, Arkhat (Proceedings of the National Academy of Sciences, 2012)
      The astonishing variation in the shape and size of bird beaks reflects a wide range of dietary specializations that played an important role in avian diversification. Among Darwin's finches, ground finches (Geospiza spp.) ...

    • Closest Conjunct Agreement in Head-Final Languages 

      Benmamoun, Elabbas; Bhatia, Archna; Polinsky, Maria (John Benjamins Publishing Company, 2009)

    • Closing in on Omega(M): The amplitude of mass fluctuations from galaxy clusters and the Ly alpha forest 

      Weinberg, D. H.; Croft, R. A. C.; Hernquist, L.; Katz, N.; Pettini, M. (American Astronomical Society, 1999)
      We estimate the present-day value of the matter density parameter Omega(M) by combining constraints from the galaxy cluster mass function with Croft et al.'s recent measurement of the mass power spectrum, P(k), from Ly ...

    • Cloud-resolving simulation of TOGA-COARE using parameterized large-scale dynamics 

      Wang, Shuguang; Sobel, Adam H.; Kuang, Zhiming (American Geophysical Union, 2013)
      Variations in deep convective activity during the 4month Tropical Ocean Global Atmosphere-Coupled Ocean Atmosphere Response Experiment (TOGA-COARE) field campaign are simulated using a cloud-resolving model (CRM). Convection ...

    • Clouds of Things Need Information Flow Control with Hardware Roots of Trust 

      Pasquier, Thomas; Singh, Jatinder; Bacon, Jean (IEEE, 2015)
      There is a clear, outstanding need for new security mechanisms that allow data to be managed and controlled within the cloud-enabled Internet of Things. Towards this, we propose an approach based on Information Flow Control ...

    • CloudSense: Continuous Fine-Grain Cloud Monitoring with Compressive Sensing 

      Kung, H. T.; Lin, Chit-Kwan; Vlah, Dario (Institute of Electrical and Electronics Engineers, 2011)
      Continuous fine-grain status monitoring of a cloud data center enables rapid response to anomalies, but handling the resulting torrent of data poses a significant challenge. As a solution, we propose CloudSense, a new ...

    • Cloudshine: New Light on Dark Clouds 

      Foster, Jonathan B.; Goodman, Alyssa A.; Foster, Jonathan; Goodman, Alyssa (American Astronomical Society, 2005)
      We present new deep near-infrared images of dark clouds in the Perseus molecular complex. These images show beautiful extended emission that we model as scattered ambient starlight and name "cloudshine." The brightness and ...

    • Cloudy with a Chance of Poaching: Adversary Behavior Modeling and Forecasting with Real-World Poaching Data 

      Kar, Debarun; Ford, Benjamin; Gholami, Shahrzad; Fang, Fei; Plumptre, Andrew; Tambe, Milind; Driciru, Margaret; Wanyama, Fred; Rwetsiba, Aggrey; Nsubaga, Mustapha; Mabonga, Joshua (ACM, 2017)
      Wildlife conservation organizations task rangers to deter and capture wildlife poachers. Since rangers are responsible for patrolling vast areas, adversary behavior modeling can help more effectively direct future patrols. ...

    • Clp-Mediated Regulation of the Mycobacterial Cell Cycle 

      Kester, Jemila Caplan (2017-04-12)
      Tuberculosis is currently the most deadly infectious disease worldwide. Given the high rates of treatment failure, new antibiotics are desperately needed. Antibacterial drugs typically target DNA replication, cell growth, ...

    • Clues to Quasar Broad-Line Region Geometry and Kinematics 

      Vestergaard, M.; Wilkes, Belinda Jane; Barthel, P. D. (IOP Publishing, 2000)
      We present evidence that the high-velocity C IV λ1549 emission-line gas of radio-loud quasars may originate in a disklike configuration, in close proximity to the accretion disk often assumed to emit the low-ionization ...