Now showing items 3642-3661 of 24506

    • Conformationally Selective RNA Aptamers Allosterically Modulate the β2-Adrenoceptor 

      Kahsai, Alem W.; Wisler, James W.; Lee, Jungmin; Ahn, Seungkirl; Cahill, Thomas J.; Dennison, S. Moses; Staus, Dean P.; Thomsen, Alex R. B.; Anasti, Kara M.; Pani, Biswaranjan; Wingler, Laura M.; Desai, Hemant; Bompiani, Kristin M.; Strachan, Ryan T.; Qin, Xiaoxia; Alam, S. Munir; Sullenger, Bruce A.; Lefkowitz, Robert J. (2016)
      G-protein-coupled receptor (GPCR) ligands function by stabilizing multiple, functionally distinct receptor conformations. This property underlies how “biased agonists” activate specific subsets of a given receptor’s signaling ...
    • Confronting 2D delayed-detonation models with light curves and spectra of Type Ia supernovae 

      Blondin, Stéphane; Kasen, Daniel; Röpke, Friedrich K.; Kirshner, Robert P.; Mandel, Kaisey S. (Oxford University Press, 2011)
      We compare models for Type Ia supernova (SN Ia) light curves and spectra with an extensive set of observations. The models come from a recent survey of 44 two-dimensional delayed-detonation models computed by Kasen et al., ...
    • Confronting Cosmological Simulations with Observations of Intergalactic Metals 

      Aguirre, Anthony; Schaye, Joop; Hernquist, Lars; Kay, Scott; Springel, Volker; Theuns, Tom (American Astronomical Society, 2005)
      Using the statistics of pixel optical depths, we compare H i, C iv, and C iii absorption in a set of six high- quality z similar to 3-4 different state- of- the- art cosmological simulations that include galactic outflows. ...
    • Confronting Maxwell's demon: biophysics of xylem embolism repair 

      Zwieniecki, Maciej A.; Holbrook, Noel Michele (Elsevier BV, 2009)
      Embolism results in a dramatic loss of xylem hydraulic transport capacity that can lead to decreased plant productivity and even death. The ability to refill embolized conduits despite the presence of tension in the xylem ...
    • Confronting Model Predictions of Carbon Fluxes with Measurements of Amazon Forests Subjected to Experimental Drought 

      Powell, Thomas L; Galbraith, David R.; Christoffersen, Bradley O.; Harper, Anna; Imbuzeiro, Hewlley M. A.; Rowland, Lucy; Almeida, Samuel; Brando, Paulo M.; da Costa, Antonio Carlos Lola; Costa, Marcos Heil; Herrera, Naomi Marcil; Malhi, Yadvinder; Saleska, Scott R.; Sotta, Eleneide; Williams, Mathew; Meir, Patrick; Moorcroft, Paul R (Wiley Blackwell, 2013)
      Considerable uncertainty surrounds the fate of Amazon rainforests in response to climate change. Here, carbon (C) flux predictions of five terrestrial biosphere models (Community Land Model version 3.5 (CLM3.5), Ecosystem ...
    • Confronting the Need for Conceptual Change in Pre-Service Science Education 

      Schwartz, Marc S.; Shapiro, Irwin I.; Gregory, Bruce (Canadian Center of Science and Education, 2013)
      During a five-year period the authors taught over 100 students in a graduate course (The Nature of Science) counting toward teacher certification at the Harvard Graduate School of Education. Despite the fact that students ...
    • Congestion Games with Distance-Based Strict Uncertainty 

      Meir, Reshef; Parkes, David C. (Association for the Advancement of Artificial Intelligence, 2015)
      We put forward a new model of congestion games where agents have uncertainty over the routes used by other agents. We take a non-probabilistic approach, assuming that each agent knows that the number of agents using an ...
    • Congressional Careers, Committee Assignments, and Seniority Randomization in the US House of Representatives 

      Kellermann, Michael; Shepsle, Kenneth A. (Now Publishers, 2009)
      This paper estimates the effects of initial committee seniority on the career histories of Democratic members of the House of Representatives from 1949 to 2006. When more than one freshman representative is assigned to a ...
    • Conjoining uncooperative societies facilitates evolution of cooperation 

      Fotouhi, Babak; Momeni, Naghmeh; Allen, Benjamin; Nowak, Martin (Springer Science and Business Media LLC, 2018-07)
      Social structure affects the emergence and maintenance of cooperation. Here, we study the evolutionary dynamics of cooperation in fragmented societies, and show that conjoining segregated cooperation-inhibiting groups, if ...
    • Conjugate Fabry–Perot Cavity Pair for Improved Astro-Comb Accuracy 

      Li, Chih-Hao; Guoqing, Chang; Glenday, Alexander G.; Langellier, Nicholas Ryan; Zibrov, Alexander S; Phillips, David Forrest; Kärtner, Franz X.; Szentgyorgyi, Andrew H.; Walsworth, Ronald L. (Optical Society of America, 2012)
      We propose a new astro-comb mode-filtering scheme composed of two Fabry–Perot cavities (coined “conjugate Fabry–Perot cavity pair”). Simulations indicate that this new filtering scheme makes the accuracy of astro-comb ...
    • Conjuring the Masses: The Figure of the Crowd in Modern Chinese Literature and Visual Culture 

      Rodekohr, Andrew Justin (2012-10-22)
      This dissertation argues that the figure of the crowd in literature and visual culture constitutes a crucial component in the emergence and construction of the cultural, political, and historical values of modern China. ...
    • Connected components of affine Deligne–Lusztig varieties in mixed characteristic 

      Chen, Miaofen; Kisin, Mark; Viehmann, Eva (Oxford University Press (OUP), 2015)
      We determine the set of connected components of minuscule affine Deligne–Lusztig varieties for hyperspecial maximal compact subgroups of unramified connected reductive groups. Partial results are also obtained for non-minuscule ...
    • Connecting Binuclear Pd(III) and Mononuclear Pd(IV) Chemistry by Pd–Pd Bond Cleavage 

      Powers, David Charles; Lee, Eunsung; Ariafard, Alireza; Sanford, Melanie S.; Yates, Brian F.; Canty, Allan J.; Ritter, Tobias (American Chemical Society, 2012)
      Oxidation of binuclear Pd(II) complexes with PhICl\(_2\) or PhI(OAc)\(_2\) has previously been shown to afford binuclear Pd(III) complexes featuring a Pd–Pd bond. In contrast, oxidation of binuclear Pd(II) complexes with ...
    • Connecting Both Sides of the “Admission Desk”: Contextual Data from High School Counselors and Factors Influencing Its Quality 

      Nicola, Tara Patricia (2023-05-08)
      In recent years, selective colleges have embraced the use of contextual data in their holistic assessments of undergraduate applicants. Background data about students’ school and home environments can enable admission ...
    • Connecting high-field quantum oscillations to zero-field electron spectral functions in the underdoped cuprates 

      Allais, Andrea; Chowdhury, Debanjan; Sachdev, Subir (Nature Publishing Group, 2014)
      The nature of the pseudogap regime of cuprate superconductors at low hole density remains unresolved. It has a number of seemingly distinct experimental signatures: a suppression of the paramagnetic spin susceptibility at ...
    • Connecting Libraries, Archives, and Museums 

      Rinaldo, Constance; Rielinger Legault, Diane; deVeer, Joseph; Castronovo, Danielle (Association for Computing Machinery (ACM), 2023-03-14)
      Over the last two decades, libraries and archives of natural history museums and botanical gardens in the US have spent major efforts to digitize their holdings. However, transporting these digitized resources from individual ...
    • The Connection between Microphysical Morphology and Atmospheric Particle Phase Transitions 

      Smith, Mackenzie Lynn (2013-02-11)
      The phase of atmospheric particles can influence heterogeneous chemistry, cloud formation, and radiative forcing. Sulfate particles ranging from sulfuric acid to ammonium sulfate are the largest contributor arising from ...
    • Connections between markets and learning 

      Chen, Yiling; Vaughan, Jennifer Wortman (Association for Computing Machinery (ACM), 2010)
      We provide an overview of recent research exploring the striking mathematical connections that exist between market maker mechanisms for prediction markets and no-regret learning. We describe how these connections can be ...
    • Connectivity and computations in higher-order olfactory neurons in Drosophila 

      Fisek, Mehmet (2014-06-06)
      Understanding how odors are encoded in the brain is of fundamental importance to neurobiology. The first two stages of olfactory information processing have been relatively well studied in both vertebrates and invertebrates. ...