Browsing Faculty of Arts and Sciences by Title

Now showing items 4481-4500 of 24540

    • Deep Eutectic-Mediated Parenteral Drug Delivery Systems for Therapeutic Macromolecules 

      Curreri, Alexander Michael (2023-06-01)
      The past 100 years have seen an evolution of drug payloads that have expanded the number of treatment options for an increasing number of treatable diseases. With this progression, it has become increasingly necessary to ...

    • Deep Genetic Divergence between Disjunct Refugia in the Arctic-Alpine King’s Crown, Rhodiola integrifolia (Crassulaceae) 

      DeChaine, Eric G.; Forester, Brenna R.; Schaefer, Hanno; Davis, Charles C. (Public Library of Science, 2013)
      Despite the strength of climatic variability at high latitudes and upper elevations, we still do not fully understand how plants in North America that are distributed between Arctic and alpine areas responded to the ...

    • The Deep History of Life 

      Knoll, Andrew Herbert (ASM Press, 2012)
      The conventional fossil record is built of hard parts—bones, shells, and decay-resistant organic tissues buried in the sediments that accumulate on floodplains, in lakes, and on the seafloor. In the 1950s, geologists first ...

    • Deep Learning for Inverse Problems in Engineering and Science 

      Tolooshams, Bahareh (2023-05-11)
      In a famous Socratic dialogue by Plato, Meno postulates that the epistemic pursuit of knowledge demands a target, without which one cannot determine the object of inquiry or even recognize it upon discovery. The paradox ...

    • Deep Learning Models for Variant Pathogenicity Prediction 

      Estanboulieh, Ralph (2021-06-04)
      Technological advancements in DNA sequencing have made it a mainstay in the clinic in the form of targeted genetic testing as well as whole exome and whole genome sequencing (WES and WGS, respectively). With increased use ...

    • Deep Predictive Coding Networks for Video Prediction and Unsupervised Learning 

      Lotter, William Edward; Kreiman, Gabriel; Cox, David Daniel (2016)
      While great strides have been made in using deep learning algorithms to solve supervised learning tasks, the problem of unsupervised learning - leveraging unlabeled examples to learn about the structure of a domain - remains ...

    • Deep Sequencing Analysis of Phage Libraries using Illumina Platform 

      Matochko, Wadim L.; Chu, Kiki; Jin, Bingjie; Lee, Sam Whan; Whitesides, George McClelland; Derda, Ratmir (Elsevier BV, 2012)
      This paper presents an analysis of phage-displayed libraries of peptides using Illumina. We describe steps for the preparation of short DNA fragments for deep sequencing and MatLab software for the analysis of the results. ...

    • Deep Sequencing and Functional Analyses Identify a Role of Fusobacterium Species in Colorectal Tumorigenesis 

      Kostic, Aleksandar David (2013-09-30)
      The tumor microenvironment is a complex community consisting of neoplastic cells, surrounding stromal cells, a broad array of immune cells, and a microbiota. By sheer numbers, the microbiota has its greatest manifestation ...

    • Deep Sequencing of Mixed Total DNA without Barcodes Allows Efficient Assembly of Highly Plastic Ascidian Mitochondrial Genomes 

      Rubinstein, Nimrod D.; Feldstein, Tamar; Shenkar, Noa; Botero-Castro, Fidel; Griggio, Francesca; Mastrototaro, Francesco; Delsuc, Frédéric; Douzery, Emmanuel J.P.; Gissi, Carmela; Huchon, Dorothée (Oxford University Press, 2013)
      Ascidians or sea squirts form a diverse group within chordates, which includes a few thousand members of marine sessile filter-feeding animals. Their mitochondrial genomes are characterized by particularly high evolutionary ...

    • Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation 

      Dueck, Hannah; Khaladkar, Mugdha; Kim, Tae Kyung; Spaethling, Jennifer M.; Francis, Chantal; Suresh, Sangita; Fisher, Stephen A.; Seale, Patrick; Beck, Sheryl G.; Bartfai, Tamas; Kuhn, Bernhard; Eberwine, James; Kim, Junhyong (BioMed Central, 2015)
      Background: Differentiation of metazoan cells requires execution of different gene expression programs but recent single-cell transcriptome profiling has revealed considerable variation within cells of seeming identical ...

    • Deep Solidarity: Political Theology, Jewish Thought, and Liberal Commitment in a Secular Age 

      Lesch, Charles (2016-09-16)
      Solidarity is crucial for liberalism. It helps to stabilize society, realize justice, diminish domination, and cultivate moral personality. Yet the sources of liberal solidarity have received almost no attention in ...

    • Deep Sparse-coded Network (DSN) 

      Gwon, Youngjune Lee; Cha, Miriam; Kung, H. T. (2015)
      We introduce Deep Sparse-coded Network (DSN), a deep architecture based on sparse coding and dictionary learning. Key advantage of our approach is two-fold. By interlacing max pooling with sparse coding layer, we achieve ...

    • Deep superconducting magnetic traps for neutral atoms and molecules 

      Harris, J. G. E.; Michniak, R. A.; Nguyen, S. V.; Campbell, W. C.; Egorov, D.; Maxwell, S. E.; van Buuren, L. D.; Doyle, John M. (AIP Publishing, 2004)
      We describe the design, construction and performance of three realizations of a high-field superconducting magnetic trap for neutral atoms and molecules. Each of these traps utilizes a pair of coaxial coils in the ...

    • Deep Xmm-newton Spectroscopic and Timing Observations of the Isolated Radio Millisecond Pulsar Psr J0030+0451 

      Bogdanov, Slavko; Grindlay, Jonathan E. (American Astronomical Society, 2009)
      We present deep XMM-Newton European Photon Imaging Camera spectroscopic and timing X-ray observations of the nearby solitary radio millisecond pulsar, PSR J0030+0451. Its emission spectrum in the 0.1-10 keV range is found ...

    • Deep-Water Incised Valley Deposits at the Ediacaran-Cambrian Boundary in Southern Namibia Contain Abundant Treptichnus Pedum 

      Knoll, Andrew Herbert; Wilson, Jonathan P.; Grotzinger, John P.; Fischer, Woodward W.; Hand, Kevin P.; Jensen, Sören; Abelson, John; Metz, Joannah M.; McLoughlin, Nicola; Cohen, Phoebe A.; Tice, Michael M. (Society for Sedimentary Geology, 2012)
      Valley-filling deposits of the Nama Group, southern Namibia, record two episodes of erosional downcutting and backfill, developed close together in time near the Ediacaran-Cambrian boundary. Geochronological constraints ...

    • The DEEP2 Galaxy Redshift Survey: Clustering of Galaxies in Early Data 

      Coil, Alison L.; Davis, Marc; Madgwick, Darren S.; Newman, Jeffrey A.; Conselice, Christopher J.; Cooper, Michael; Ellis, Richard S.; Faber, S. M.; Finkbeiner, Douglas; Guhathakurta, Puragra; Kaiser, Nick; Koo, David C.; Phillips, Andrew C.; Steidel, Charles C.; Weiner, Benjamin J.; Willmer, Christopher N. A.; Yan, Renbin (IOP Publishing, 2004)
      We measure the two-point correlation function ξ(rp, π) in a sample of 2219 galaxies between z = 0.7 and 1.35 to a magnitude limit of RAB = 24.1 from the first season of the DEEP2 Galaxy Redshift Survey. From ξ(rp, π) we ...

    • The DEEP2 Galaxy Redshift Survey: Design, Observations, Data Reduction, and Redshifts 

      Newman, Jeffrey A.; Cooper, Michael C.; Davis, Marc; Faber, S. M.; Coil, Alison L.; Guhathakurta, Puragra; Koo, David C.; Phillips, Andrew C.; Conroy, Charlie; Dutton, Aaron A.; Finkbeiner, Douglas; Gerke, Brian F.; Rosario, David J.; Weiner, Benjamin J.; Willmer, C. N. A.; Yan, Renbin; Harker, Justin J.; Kassin, Susan A.; Konidaris, N. P.; Lai, Kamson; Madgwick, Darren S.; Noeske, K. G.; Wirth, Gregory D.; Connolly, A. J.; Kaiser, N.; Kirby, Evan N.; Lemaux, Brian C.; Lin, Lihwai; Lotz, Jennifer M.; Luppino, G. A.; Marinoni, C.; Matthews, Daniel J.; Metevier, Anne; Schiavon, Ricardo P. (IOP Publishing, 2013)
      We describe the design and data analysis of the DEEP2 Galaxy Redshift Survey, the densest and largest high-precision redshift survey of galaxies at z ~ 1 completed to date. The survey was designed to conduct a comprehensive ...

    • The DEEP2 Galaxy Redshift Survey: First Results on Galaxy Groups 

      Gerke, Brian F.; Newman, Jeffrey A.; Davis, Marc; Marinoni, Christian; Yan, Renbin; Coil, Alison L.; Conroy, Charlie; Cooper, Michael C.; Faber, S. M.; Finkbeiner, Douglas; Guhathakurta, Puragra; Kaiser, Nick; Koo, David C.; Phillips, Andrew C.; Weiner, Benjamin J.; Willmer, Christopher N. A. (IOP Publishing, 2005)
      We use the first 25% of the DEEP2 Galaxy Redshift Survey spectroscopic data to identify groups and clusters of galaxies in redshift space. The data set contains 8370 galaxies with confirmed redshifts in the range 0.7 ≤ z ...

    • The DEEP2 Galaxy Redshift Survey: the relationship between galaxy properties and environment at z  1 

      Cooper, M. C.; Newman, J. A.; Croton, D. J.; Weiner, B. J.; Willmer, C. N. A.; Gerke, B. F.; Madgwick, D. S.; Faber, S. M.; Davis, M.; Coil, A. L.; Finkbeiner, Douglas; Guhathakurta, P.; Koo, D. C. (Oxford University Press (OUP), 2006)
      We study the mean environment of galaxies in the DEEP2 Galaxy Redshift Survey as a function of rest-frame colour, luminosity, and [O-ii] 3727-Å equivalent width. The local galaxy overdensity for >14-000 galaxies at 0.75 < ...

    • Defect-mediated dynamics of coherent structures in active nematics 

      Serra, Mattia; Lemma, Linnea; Giomi, Luca; Dogic, Zvonimir; Mahadevan, Lakshminarayanan (Springer Science and Business Media LLC, 2023-05-25)
      Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topo- logical defects. By contrast, little ...