Browsing Faculty of Arts and Sciences by Title
Now showing items 498-517 of 24540
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An additive framework for kirigami design
(Springer Science and Business Media LLC, 2023-05-25)We present an additive approach for the inverse design of kirigami-based mechanical metamaterials by focusing on the empty (negative) spaces instead of the solid tiles. By considering each negative space as a four-bar ... -
Additive Theories of Rationality: A Critique
(Wiley, 2012-04-28)“Additive theories” of rationality, as I use the term, are views that hold that an account of our minds can begin with an account of what it is to perceive and desire, in terms which do not presuppose any connection to the ... -
Addressing Missing Data in Viral Genetic Linkage Analysis Through Multiple Imputation and Subsampling-Based Likelihood Optimization
(2015-06-26)This thesis addresses the intersection of two important areas in epidemiology and statistics: genetic linkage analysis and missing data methods, respectively. Genetic linkage analysis is a promising method in viral ... -
Addressing pharmacological challenges to the treatment of pediatric brain tumors using modern technology
(2021-07-12)Despite decades of research, several obstacles remain a challenge to effectively treat and manage pediatric brain tumors. Tumor type, drug delivery, and drug distribution are three factors that contribute to the obstacles ... -
Addressing Recognition Gaps: Destigmatization and the Reduction of Inequality
(SAGE Publications, 2018-05-21)This Presidential Address offers elements for a systematic and cumulative study of destigmatization, or the process by which low-status groups gain recognition and worth. Contemporary sociologists tend to focus on inequality ... -
Addressing Underspecified Lineage Queries on Provenance
(2011)State-of-the-art provenance systems accumulate data over time, creating deep lineage trees. When queried for the lineage of an object, these systems can return excessive results due to the longevity and depth of their ... -
Addressing Urban Stormwater Management Under Climate Change: a Case Study of Cambridge
(2017-07-13)Stormwater management relies on methods of prediction and modeling to inform decisions on risk-based infrastructure. As climate change threatens disrupt and exacerbate weather conditions, the methodologies of single-event ... -
Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication
(Proceedings of the National Academy of Sciences, 2012)Diabetes is a pathological condition characterized by relative insulin deficiency, persistent hyperglycemia, and, consequently, diffuse micro- and macrovascular disease. One therapeutic strategy is to amplify insulin-secretion ... -
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
(The Rockefeller University Press, 2015)Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT remain poorly understood. Here, we show that ... -
Adherence to the Mediterranean diet and body fat distribution in reproductive aged women
(2013)Background/Objectives Adherence to the Mediterranean Diet (MD) high in fruits, vegetables and monounsaturated fats, has been associated with lower body mass index. Associations with measured body fat, including regional ... -
Adhesion Degradation and Water Diffusion in Nanoporous Organosilicate Glass Thin Film Stacks
(The Electrochemical Society, 2010)The diffusion of water in nanoporous organosilicate glass (NPOSG) film stacks causes significant adhesion degradation of the capping layer on top of the NPOSG. We have used this adhesion degradation to estimate the diffusivity ... -
Adiabatic Preparation of Many-Body States in Optical Lattices
(American Physical Society, 2010)We analyze a technique for the preparation of low-entropy many-body states of atoms in optical lattices based on adiabatic passage. In particular, we show that this method allows preparation of strongly correlated states ... -
Adiabatic quantum optimization in the presence of discrete noise: Reducing the problem dimensionality
(American Physical Society (APS), 2015)Adiabatic quantum optimization is a procedure to solve a vast class of optimization problems by slowly changing the Hamiltonian of a quantum system. The evolution time necessary for the algorithm to be successful scales ... -
Adiabatic Quantum Search in Open Systems
(American Physical Society, 2016)Adiabatic quantum algorithms represent a promising approach to universal quantum computation. In isolated systems, a key limitation to such algorithms is the presence of avoided level crossings, where gaps become extremely ... -
Adiabatic Quantum Simulation of Quantum Chemistry
(Nature Publishing Group, 2014)We show how to apply the quantum adiabatic algorithm directly to the quantum computation of molecular properties. We describe a procedure to map electronic structure Hamiltonians to 2-body qubit Hamiltonians with a small ...