Browsing Faculty of Arts and Sciences by Title
Now showing items 8088-8107 of 24540
-
Fgd5 identifies hematopoietic stem cells in the murine bone marrow
(The Rockefeller University Press, 2014)Hematopoietic stem cells (HSCs) are the best-characterized tissue-specific stem cells, yet experimental study of HSCs remains challenging, as they are exceedingly rare and methods to purify them are cumbersome. Moreover, ... -
FGF-23–Klotho signaling stimulates proliferation and prevents vitamin D–induced apoptosis
(Rockefeller University Press, 2008)Fibroblast growth factor 23 (FGF-23) and Klotho are secretory proteins that regulate mineral-ion metabolism. Fgf-23(-/-) or Klotho(-/-) knockout mice exhibit several pathophysiological processes consistent with premature ... -
Fiber Four-Wave Mixing Source for Coherent Anti-Stokes Raman Scattering Microscopy
(The Optical Society, 2012)We present a fiber-format picosecond light source for coherent anti-Stokes Raman scattering microscopy. Pulses from an Yb-doped fiber amplifier are frequency-converted by four-wave mixing in normal dispersion photonic ... -
Fiber Optic Projection-Imaging System for Shape Measurement in Confined Space
(Hindawi Publishing Corporation, 2014)A fiber-based projection-imaging system is proposed for shape measurement in confined space. Owing to the flexibility of imaging fibers, the system can be used in special scenarios that are difficult for conventional ... -
Fiber-reinforced tough hydrogels
(Elsevier BV, 2014)Using strong fibers to reinforce a hydrogel is highly desirable but difficult. Such a composite would combine the attributes of a solid that provides strength and a liquid that transports matter. Most hydrogels, however, ... -
Fiber-seq reveals the single-molecule architecture of nuclear transcription and the mitochondrial genome
(2024-01-11)Gene regulation is driven by the interplay of numerous features including regulatory factors, genome packaging, and the transcriptional machinery. Established approaches to characterize these features on a genomic scale ... -
Fibroblast Growth Factor–23 and Cardiac Structure and Function
(Blackwell Publishing Ltd, 2014)Background: Fibroblast growth factor–23 (FGF‐23) is a phosphaturic factor previously associated with left ventricular hypertrophy and systolic dysfunction among individuals with chronic kidney disease. Whether FGF‐23 acts ... -
Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions
(Wiley Subscription Services, Inc., A Wiley Company, 2009)Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the ... -
Fibroblasts Derived from Human Pluripotent Stem Cells Activate Angiogenic Responses In Vitro and In Vivo
(Public Library of Science, 2013)Human embryonic and induced pluripotent stem cells (hESC/hiPSC) are promising cell sources for the derivation of large numbers of specific cell types for tissue engineering and cell therapy applications. We have describe ... -
Fibroblasts Enhance Migration of Human Lung Cancer Cells in a Paper-Based Coculture System
(Wiley-Blackwell, 2015)A multilayered paper-based platform is used to investigate the interactions between human lung tumor cells and fibroblasts that are isolated from primary patient tumor samples. -
Fibronectin Unfolding Revisited: Modeling Cell Traction-Mediated Unfolding of the Tenth Type-III Repeat
(Public Library of Science, 2008)Fibronectin polymerization is essential for the development and repair of the extracellular matrix. Consequently, deciphering the mechanism of fibronectin fibril formation is of immense interest. Fibronectin fibrillogenesis ... -
Ficino's Critique of Lucretius
(Istituto Nazionale di Studi sul Rinascimento and The Harvard University Center for Italian Renaissance Studies, 2010-02-18)After an early flirtation with Lucretius, Marsilio Ficino, the leading Platonic philosopher of the Renaissance, became a confirmed enemy of the Epicurean philosopher. This chapter discusses the extensive critique of Lucretius ... -
Ficino, Avicenna and the Occult Powers of the Rational Soul
(Leo S. Olschki, 2007)Argues that the received account of Ficino's magic, that it is a gentle, natural or spiritus-based magic, are inadequate and that in some little-read passages of his Platonic Theology Ficino revealed his belief in the ... -
Fiction's Metronomes: Music, Time, and the Eighteenth-Century British Novel
(2021-05-14)While the British novel emerges in a century increasingly governed by clocks and schedules, it not only assumes a variety of temporal shapes but also grapples with the antinomies of time as at once countable and defying ... -
Fidelity of climate data: Trends, extremes, and nonlinearities in instrumental and tree-growth proxies of climate
(2023-01-12)This work looks at inferences of climate -- and specifically moisture and temperature --, past and present. In the present, asks whether we have enough data to understand extremes in temperature and trends in moisture. ... -
Fidelity, Fairness and Responsibility through the Lens of Sequential Decision Making
(2024-01-19)As methods of artificial intelligence continue to become increasingly important to support robust decision making in regard to deciding how to act on the basis of the right data, learning to act over time while supporting ... -
Field Experiments in Behavioral and Public Economics
(2015-05-11)The three essays in this dissertation present field experiments exploring phenomena in behavioral and public economics in real-world settings. The first essay outlines a field experiment that uses mailers with peer rank ... -
Field experiments on solar geoengineering: report of a workshop exploring a representative research portfolio
(The Royal Society Publishing, 2014)We summarize a portfolio of possible field experiments on solar radiation management (SRM) and related technologies. The portfolio is intended to support analysis of potential field research related to SRM including ... -
Field fluctuations measured by interferometry
(IOP Publishing, 2010)We derive the complete photon count statistics of an interferometer based on two beam splitters. As a special case we consider a joint intensity–electric field measurement. Our approach is based on the transformation ... -
A Field Guide to The Limb Progenitor
(2016-05-16)The primary goal of this thesis was to characterize the embryonic limb progenitor, a cell type that populates the early limb bud during the onset of limb morphogenesis. Two features of the limb progenitor were explored 1) ...