Browsing Faculty of Arts and Sciences by Title

Now showing items 9003-9022 of 24540

    • GeNets: A unified web platform for network-based analyses of genomic data 

      Li, Taibo; Kim, April; Rosenbluh, Joseph; Horn, Heiko; Greenfeld, Liraz; An, David; Zimmer, Andrew; Liberzon, Arthur; Bistline, Jon; Natoli, Ted; Li, Yang; Tsherniak, Aviad; Narayan, Rajiv; Subramanian, Aravind; Liefeld, Ted; Wong, Bang; Thompson, Dawn; Calvo, Sarah; Carr, Steve; Boehm, Jesse; Jaffe, Jake; Mesirov, Jill; Hacohen, Nir; Regev, Aviv; Lage, Kasper

    • Genitals evolve faster than other traits in Anolis lizards 

      Klaczko, Julia; Ingram, Ty; Losos, Jonathan (Wiley-Blackwell, 2015)

    • Genjo sanzo no toei (Tripitaka master Xuanzang and his reflections) 

      Abe, Ryuichi (Seikansha Press, 2015)

    • Genome Analyses of Single Human Oocytes 

      Hou, Yu; Fan, Wei; Yan, Liying; Li, Rong; Lian, Ying; Huang, Jin; Li, Jinsen; Xu, Liya; Tang, Fuchou; Xie, Xiaoliang Sunney; Qiao, Jie (Elsevier BV, 2013)
      Single-cell genome analyses of human oocytes are important for meiosis research and preimplantation genomic screening. However, the nonuniformity of single-cell whole-genome amplification hindered its use. Here, we demonstrate ...

    • Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii 

      Seim, Inge; Fang, Xiaodong; Xiong, Zhiqiang; Lobanov, Alexey V.; Huang, Zhiyong; Ma, Siming; Feng, Yue; Turanov, Anton A.; Zhu, Yabing; Lenz, Tobias L.; Gerashchenko, Maxim V.; Fan, Dingding; Hee Yim, Sun; Yao, Xiaoming; Jordan, Daniel; Xiong, Yingqi; Ma, Yong; Lyapunov, Andrey N.; Chen, Guanxing; Kulakova, Oksana I.; Sun, Yudong; Lee, Sang-Goo; Bronson, Roderick T.; Moskalev, Alexey A.; Sunyaev, Shamil R.; Zhang, Guojie; Krogh, Anders; Wang, Jun; Gladyshev, Vadim N. (Nature Pub. Group, 2013)
      Bats account for one-fifth of mammalian species, are the only mammals with powered flight, and are among the few animals that echolocate. The insect-eating Brandt’s bat (Myotis brandtii) is the longest-lived bat species ...

    • A Genome Assembly-Integrated Dog 1 Mb BAC Microarray: A Cytogenetic Resource for Canine Cancer Studies and Comparative Genomic Analysis 

      Thomas, R.; Duke, S. E.; Karlsson, Elinor Kathryn; Evans, A.; Ellis, P.; Lindblad-Toh, K.; Langford, C.F.; Breen, M. (Karger, 2008)
      Molecular cytogenetic studies have been instrumental in defining the nature of numerical and structural chromosome changes in human cancers, but their significance remains to be fully understood. The emergence of high ...

    • Genome Engineering Technologies to Change the Genetic Code 

      Lajoie, Marc Joseph (2014-02-25)
      New technologies are making it possible to engineer organisms with fundamentally new and useful properties. In vivo genome engineering technologies capable of manipulating genomes from the nucleotide to the megabase scale ...

    • Genome Engineering Technology and Its Application in Mammalian Cells 

      Cong, Le (2014-06-06)
      The advancement of high-throughput, large-scale biochemical, biophysical, and genetic technologies has enabled the generation of massive amounts of biological data and allowed us to synthesize various types of biomaterial ...

    • Genome Evolution in Reptilia: in silico Chicken Mapping of 12,000 BAC-end Sequences from Two Reptiles and a Basal Bird 

      Chapus, Charles; Edwards, Scott V. (BioMed Central, 2009)
      Background: With the publication of the draft chicken genome and the recent production of several BAC clone libraries from non-avian reptiles and birds, it is now possible to undertake more detailed comparative genomic ...

    • Genome evolution in structured systems 

      Chung, Hattie (2016-05-14)
      The evolution of a genome is shaped by spatial interactions at multiple scales. At the angstrom level, structural constraints on both RNA molecules and proteins contribute to the evolution of a gene sequence. Such optimized ...

    • Genome Features of “Dark-Fly”, a Drosophila Line Reared Long-Term in a Dark Environment 

      Izutsu, Minako; Zhou, Jun; Sugiyama, Yuzo; Nishimura, Osamu; Aizu, Tomoyuki; Toyoda, Atsushi; Fujiyama, Asao; Agata, Kiyokazu; Fuse, Naoyuki (Public Library of Science, 2012)
      Organisms are remarkably adapted to diverse environments by specialized metabolisms, morphology, or behaviors. To address the molecular mechanisms underlying environmental adaptation, we have utilized a Drosophila melanogaster ...

    • Genome Landscapes and Bacteriophage Codon Usage 

      Lucks, Julius B.; Nelson, David R.; Kudla, Grzegorz R.; Plotkin, Joshua B.; Regev, Aviv (Public Library of Science, 2008)
      Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonymous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes ...

    • The genome of the green anole lizard and a comparative analysis with birds and mammals 

      Alföldi, Jessica; Di Palma, Federica; Grabherr, Manfred; Williams, Christina; Kong, Lesheng; Mauceli, Evan; Russell, Pamela; Lowe, Craig B.; Glor, Richard E.; Jaffe, Jacob D.; Ray, David A.; Boissinot, Stephane; Shedlock, Andrew M.; Botka, Christopher; Castoe, Todd A.; Colbourne, John K.; Fujita, Matthew; Moreno, Ricardo Godinez; ten Hallers, Boudewijn F.; Haussler, David; Heger, Andreas; Heiman, David; Janes, Daniel E.; Johnson, Jeremy; de Jong, Pieter J.; Koriabine, Maxim Y.; Lara, Marcia; Novick, Peter A.; Organ, Chris L.; Peach, Sally E.; Poe, Steven; Pollock, David D.; de Queiroz, Kevin; Sanger, Thomas; Searle, Steve; Smith, Jeremy D.; Smith, Zachary; Swofford, Ross; Turner-Maier, Jason; Wade, Juli; Young, Sarah; Zadissa, Amonida; Edwards, Scott V.; Glenn, Travis C.; Schneider, Christopher; Losos, Jonathan; Lander, Eric Steven; Breen, Matthew; Ponting, Chris P.; Lindblad-Toh, Kerstin (Nature Publishing Group, 2011)
      The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. ...

    • Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment 

      Scott, Jeffrey G; Warren, Wesley C; Beukeboom, Leo W; Bopp, Daniel; Clark, Andrew G; Giers, Sarah D; Hediger, Monika; Jones, Andrew K; Kasai, Shinji; Leichter, Cheryl A; Li, Ming; Meisel, Richard P; Minx, Patrick; Murphy, Terence D; Nelson, David R; Reid, William R; Rinkevich, Frank D; Robertson, Hugh M; Sackton, Timothy B; Sattelle, David B; Thibaud-Nissen, Francoise; Tomlinson, Chad; van de Zande, Louis; Walden, Kimberly KO; Wilson, Richard K; Liu, Nannan (BioMed Central, 2014)
      Background: Adult house flies, Musca domestica L., are mechanical vectors of more than 100 devastating diseases that have severe consequences for human and animal health. House fly larvae play a vital role as decomposers ...

    • The genome of the intracellular bacterium of the coastal bivalve, Solemya velum: a blueprint for thriving in and out of symbiosis 

      Dmytrenko, Oleg; Russell, Shelbi L; Loo, Wesley T; Fontanez, Kristina M; Liao, Li; Roeselers, Guus; Sharma, Raghav; Stewart, Frank J; Newton, Irene LG; Woyke, Tanja; Wu, Dongying; Lang, Jenna Morgan; Eisen, Jonathan A; Cavanaugh, Colleen M (BioMed Central, 2014)
      Background: Symbioses between chemoautotrophic bacteria and marine invertebrates are rare examples of living systems that are virtually independent of photosynthetic primary production. These associations have evolved ...

    • Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels 

      van Leeuwen, Elisabeth M.; Karssen, Lennart C.; Deelen, Joris; Isaacs, Aaron; Medina-Gomez, Carolina; Mbarek, Hamdi; Kanterakis, Alexandros; Trompet, Stella; Postmus, Iris; Verweij, Niek; van Enckevort, David J.; Huffman, Jennifer E.; White, Charles C.; Feitosa, Mary F.; Bartz, Traci M.; Manichaikul, Ani; Joshi, Peter K.; Peloso, Gina M.; Deelen, Patrick; van Dijk, Freerk; Willemsen, Gonneke; de Geus, Eco J.; Milaneschi, Yuri; Penninx, Brenda W.J.H.; Francioli, Laurent C.; Menelaou, Androniki; Pulit, Sara L.; Rivadeneira, Fernando; Hofman, Albert; Oostra, Ben A.; Franco, Oscar H.; Leach, Irene Mateo; Beekman, Marian; de Craen, Anton J.M.; Uh, Hae-Won; Trochet, Holly; Hocking, Lynne J.; Porteous, David J.; Sattar, Naveed; Packard, Chris J.; Buckley, Brendan M.; Brody, Jennifer A.; Bis, Joshua C.; Rotter, Jerome I.; Mychaleckyj, Josyf C.; Campbell, Harry; Duan, Qing; Lange, Leslie A.; Wilson, James F.; Hayward, Caroline; Polasek, Ozren; Vitart, Veronique; Rudan, Igor; Wright, Alan F.; Rich, Stephen S.; Psaty, Bruce M.; Borecki, Ingrid B.; Kearney, Patricia M.; Stott, David J.; Adrienne Cupples, L.; Neerincx, Pieter B.T.; Elbers, Clara C.; Francesco Palamara, Pier; Pe'er, Itsik; Abdellaoui, Abdel; Kloosterman, Wigard P.; van Oven, Mannis; Vermaat, Martijn; Li, Mingkun; Laros, Jeroen F.J.; Stoneking, Mark; de Knijff, Peter; Kayser, Manfred; Veldink, Jan H.; van den Berg, Leonard H.; Byelas, Heorhiy; den Dunnen, Johan T.; Dijkstra, Martijn; Amin, Najaf; Joeri van der Velde, K.; van Setten, Jessica; Kattenberg, Mathijs; van Schaik, Barbera D.C.; Bot, Jan; Nijman, Isaäc J.; Mei, Hailiang; Koval, Vyacheslav; Ye, Kai; Lameijer, Eric-Wubbo; Moed, Matthijs H.; Hehir-Kwa, Jayne Y.; Handsaker, Robert E.; Sunyaev, Shamil R.; Sohail, Mashaal; Hormozdiari, Fereydoun; Marschall, Tobias; Schönhuth, Alexander; Guryev, Victor; Suchiman, H. Eka D.; Wolffenbuttel, Bruce H.; Platteel, Mathieu; Pitts, Steven J.; Potluri, Shobha; Cox, David R.; Li, Qibin; Li, Yingrui; Du, Yuanping; Chen, Ruoyan; Cao, Hongzhi; Li, Ning; Cao, Sujie; Wang, Jun; Bovenberg, Jasper A.; Jukema, J. Wouter; van der Harst, Pim; Sijbrands, Eric J.; Hottenga, Jouke-Jan; Uitterlinden, Andre G.; Swertz, Morris A.; van Ommen, Gert-Jan B.; de Bakker, Paul I.W.; Eline Slagboom, P.; Boomsma, Dorret I.; Wijmenga, Cisca; van Duijn, Cornelia M. (Nature Pub. Group, 2015)
      Variants associated with blood lipid levels may be population-specific. To identify low-frequency variants associated with this phenotype, population-specific reference panels may be used. Here we impute nine large Dutch ...

    • Genome Organization and Gene Expression Shape the Transposable Element Distribution in the Drosophila Melanogaster Euchromatin 

      Fontanillas, Pierre; Hartl, Daniel L.; Reuter, Max; Malik, Harmit S (Public Library of Science, 2007)
      The distribution of transposable elements (TEs) in a genome reflects a balance between insertion rate and selection against new insertions. Understanding the distribution of TEs therefore provides insights into the forces ...

    • Genome Sequence of Streptomyces sp. Strain RTd22, an Endophyte of the Mexican Sunflower 

      Chagas, Fernanda O.; Ruzzini, Antonio C.; Bacha, Larissa V.; Samborskyy, Markyian; Conti, Raphael; Pessotti, Rita C.; de Oliveira, Luciana G.; Clardy, Jon; Pupo, Monica T. (American Society for Microbiology, 2016)
      We report here the complete genome sequence of Streptomyces sp. strain RTd22, an endophytic actinobacterium that was isolated from the roots of the Mexican sunflower Tithonia diversifolia. The bacterium’s 11.1-Mb linear ...

    • Genome Sequences of Three Pseudoalteromonas Strains (P1-8, P1-11, and P1-30), Isolated from the Marine Hydroid Hydractinia echinata 

      Klassen, Jonathan L.; Rischer, Maja; Wolf, Thomas; Guo, Huijuan; Shelest, Ekaterina; Clardy, Jon; Beemelmanns, Christine (American Society for Microbiology, 2015)
      The genomes of three Pseudoalteromonas strains (P1-8, P1-11, and P1-30) were sequenced and assembled. These genomes will inform future study of the genes responsible for the production of biologically active compounds ...

    • Genome-Scale DNA Methylation Analysis in Distinct Pluripotent Stem Cells 

      Webster, Jamie Orme (2014-06-06)
      Mouse embryonic stem cells (ESCs) and embryonic germ cells (EGCs) are both pluripotent cell types derived from distinct developmental stages. Despite sharing many characteristics, some differences have been reported between ...