Browsing Faculty of Arts and Sciences by Keyword "CD8 T cell"
Now showing items 1-2 of 2
-
Characterization of the Mamu-A*01-Restricted CD8-Positive T Lymphocyte Immunodominance Hierarchy in Simian Immunodeficiency Virus-Infected Rhesus Monkeys
(2012-10-29)\(CD8^+\) cytotoxic T lymphocytes (CTLs) play a critical role in controlling human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication. The CTL responses that are thought to be the most protective ... -
Deletion of an exhaustion-specific PD-1 enhancer modulates CD8+ T cell fate and function
(2022-09-06)Exhaustion is a state of CD8+ T cell dysfunction arising during chronic viral infection and cancer. Exhausted T cells are less proliferative and less cytotoxic, produce less cytokine, and express high levels of co-inhibitory ...