Browsing Faculty of Arts and Sciences by Keyword "DNA supercoiling"
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Detection of Single-Molecule Optical Absorption at Room Temperature and Mechanistic Study of Transcriptional Bursting
(2014-06-06)Advances in optical imaging techniques have allowed quantitative studies of many biological systems. This dissertation elaborates on our efforts in both developing novel imaging modalities based on detection of optical ... -
Toward a Sensor for DNA Supercoiling
(2023-06-30)DNA in the cell takes on a double helical structure that is then formed into larger loops, compacting into a supercoil. These supercoils are the result of mechanical torsional forces caused by over or underwound DNA. ...