Browsing Faculty of Arts and Sciences by Keyword "Hematology"

Now showing items 1-6 of 6

    • Anemia at the Initiation of Tuberculosis Therapy Is Associated with Delayed Sputum Conversion among Pulmonary Tuberculosis Patients in Dar-es-Salaam, Tanzania 

      Nagu, Tumaini J.; Spiegelman, Donna; Hertzmark, Ellen; Aboud, Said; Makani, Julie; Matee, Mecky I.; Fawzi, Wafaie; Mugusi, Ferdinand (Public Library of Science, 2014)
      Background: Pulmonary tuberculosis and anemia are both prevalent in Tanzania. There is limited and inconsistent literature on the association between anemia and sputum conversion following tuberculosis treatment. Methods: ...

    • Cationic Peptide Exposure Enhances Pulsed-Electric-Field-Mediated Membrane Disruption 

      Kennedy, Stephen M.; Aiken, Erik J.; Beres, Kaytlyn A.; Hahn, Adam R.; Kamin, Samantha J.; Hagness, Susan C.; Booske, John H.; Murphy, William L. (Public Library of Science, 2014)
      Background: The use of pulsed electric fields (PEFs) to irreversibly electroporate cells is a promising approach for destroying undesirable cells. This approach may gain enhanced applicability if the intensity of the PEF ...

    • Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia 

      Kumar, Ashok A.; Chunda-Liyoka, Catherine; Hennek, Jonathan W.; Mantina, Hamakwa; Lee, S. Y. Ryan; Patton, Matthew R.; Sambo, Pauline; Sinyangwe, Silvester; Kankasa, Chipepo; Chintu, Chifumbe; Brugnara, Carlo; Stossel, Thomas P.; Whitesides, George M. (Public Library of Science, 2014)
      Although simple and low-cost interventions for sickle cell disease (SCD) exist in many developing countries, child mortality associated with SCD remains high, in part, because of the lack of access to diagnostic tests for ...

    • Induction of Histiocytic Sarcoma in Mouse Skeletal Muscle 

      Liu, Jianing; Hettmer, Simone; Milsom, Michael D.; Hofmann, Inga; Hua, Frederic; Miller, Christine; Bronson, Roderick Terry; Wagers, Amy Jo (Public Library of Science, 2012)
      Myeloid sarcomas are extramedullary accumulations of immature myeloid cells that may present with or without evidence of pathologic involvement of the bone marrow or peripheral blood, and often coincide with or precede a ...

    • Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy 

      Cox, Aaron R.; Barrandon, Ornella; Cai, Erica P.; Rios, Jacqueline S.; Chavez, Julia; Bonnyman, Claire W.; Lam, Carol J.; Yi, Peng; Melton, Douglas A.; Kushner, Jake A. (Public Library of Science, 2016)
      The β-cell mitogenic effects of ANGPTL8 have been subjected to substantial debate. The original findings suggested that ANGPTL8 overexpression in mice induced a 17-fold increase in β-cell proliferation. Subsequent studies ...

    • Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label 

      Carlson, Alicia L.; Fujisaki, Joji; Wu, Juwell; Runnels, Judith M.; Turcotte, Raphaël; Celso, Cristina Lo; Scadden, David T.; Strom, Terry B.; Lin, Charles P. (Public Library of Science, 2013)
      We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after ...