Browsing Faculty of Arts and Sciences by Keyword "ICP0"
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Inhibition of Nuclear DNA Sensing by Herpes Simplex Virus 1
(2013-10-08)The detection of immunostimulatory DNA is well documented to occur at several cellular sites, but there is limited evidence of nuclear innate DNA sensing. Prior to this study, the detection of herpesviral DNA was thought ... -
A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes
(MDPI, 2014)Herpes simplex virus type 1 (HSV-1) is a significant human pathogen that infects a large portion of the human population. Cells deploy a variety of defenses to limit the extent to which the virus can replicate. One such ...