Browsing Faculty of Arts and Sciences by Keyword "cell cycle"
Now showing items 1-5 of 5
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Dynamic regulation of histone lysine methylation via the ubiquitin-proteasome system.
(2013-10-18)Lysine methylation is an important post-translational modification found on histones that is added and removed by histone lysine methyltransferases and demethylases, respectively. Lysine methylation occurs in a specific ... -
Genome-Wide Loss-of-Function Genetic Screens Identify Novel Senescence Genes and Putative Tumor Suppressors
(2013-02-22)During every cell cycle and upon exogenous stress, tumor suppression programs are engaged to ensure genomic stability. In response to replicative aging and oncogenic stimuli, the p53 and Rb pathways are activated to prevent ... -
Inhibition of Cdc42 during mitotic exit is required for cytokinesis in Saccharomyces cerevisiae
(2014-02-25)Rho GTPases are highly conserved regulators of cell polarity and the actin cytoskeleton. The role of the Rho GTPase Cdc42 and its regulation during cell division is not well understood. Using biochemical and imaging ... -
Simultaneous regulation of cell size and chromosome replication in bacteria
(Frontiers Media S.A., 2015)Bacteria are able to maintain a narrow distribution of cell sizes by regulating the timing of cell divisions. In rich nutrient conditions, cells divide much faster than their chromosomes replicate. This implies that cells ... -
Understanding responses to chemical and environmental perturbations in blood stage Babesia parasites
(2022-05-05)Babesiosis is a disease caused by apicomplexan parasites related to the malaria parasite Plasmodium. Like Plasmodium, Babesia infects red blood cells (RBCs) in the host animal. Babesia is one of the most widespread blood ...