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    • Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing 

      Ding, Q.; Strong, A.; Patel, K. M.; Ng, S.-L.; Gosis, Bridget Stephanie; Regan, Stephanie N.; Cowan, Chad A.; Rader, D. J.; Musunuru, Kiran (Ovid Technologies (Wolters Kluwer Health), 2014)
      Rationale: Individuals with naturally occurring loss-of-function proprotein convertase subtilisin/kexin type 9 (PCSK9) mutations experience reduced low-density lipoprotein cholesterol levels and protection against ...