Browsing Faculty of Arts and Sciences by Keyword "driver mutation"

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    • The effect of one additional driver mutation on tumor progression 

      Reiter, Johannes G; Bozic, Ivana; Allen, Benjamin Isaac; Chatterjee, Krishnendu; Nowak, Martin A. (Blackwell Publishing Ltd, 2013)
      Tumor growth is caused by the acquisition of driver mutations, which enhance the net reproductive rate of cells. Driver mutations may increase cell division, reduce cell death, or allow cells to overcome density-limiting ...