Browsing Faculty of Arts and Sciences by Keyword "gene targeting"
Now showing items 1-2 of 2
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An Embryonic Stem Cell-Based System for Rapid Analysis of Transcriptional Enhancers
(Wiley Periodicals, Inc., 2012)With the growing use of genome-wide screens for cis-regulatory elements, there is a pressing need for platforms that enable fast and cost-effective experimental validation of identified hits in relevant developmental and ... -
Genetic Targeting of the Endoderm with Claudin-6CreER
(Wiley-Blackwell, 2008)A full description of the ontogeny of the β cell would guide efforts to generate β cells from embryonic stem cells (ESCs). The first step requires an understanding of definitive endoderm: the genes and signals responsible ...