Browsing Faculty of Arts and Sciences by Keyword "germ cells"
Now showing items 1-4 of 4
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Characterization of transcription factor function during human gametogenesis via directed differentiation
(2022-06-06)It is estimated that one in ten people in the US struggle with infertility. Access to human germline cell types for study is limited, and little is known about the underlying genetic regulation of human gametogenesis. In ... -
Csm4, in Collaboration with Ndj1, Mediates Telomere-Led Chromosome Dynamics and Recombination during Yeast Meiosis
(Public Library of Science, 2008)Chromosome movements are a general feature of mid-prophase of meiosis. In budding yeast, meiotic chromosomes exhibit dynamic movements, led by nuclear envelope (NE)-associated telomeres, throughout the zygotene and pachytene ... -
A premeiotic function forboulein the planarianSchmidtea mediterranea
(Proceedings of the National Academy of Sciences, 2016)Mutations in Deleted in Azoospermia (DAZ), a Y chromosome gene, are an important cause of human male infertility. DAZ is found exclusively in primates, limiting functional studies of this gene to its homologs: boule, ... -
Reversible Disassembly of the Actin Cytoskeleton Improves the Survival Rate and Developmental Competence of Cryopreserved Mouse Oocytes
(Public Library of Science, 2008)Effective cryopreservation of oocytes is critically needed in many areas of human reproductive medicine and basic science, such as stem cell research. Currently, oocyte cryopreservation has a low success rate. The goal of ...