Browsing Faculty of Arts and Sciences by Keyword "insertional mutagenesis"
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Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions
(Wiley Subscription Services, Inc., A Wiley Company, 2009)Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the ...