Dual-Modality Fluorescence and Full-Field Optical Coherence Microscopy for Biomedical Imaging Applications

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Dual-Modality Fluorescence and Full-Field Optical Coherence Microscopy for Biomedical Imaging Applications

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Title: Dual-Modality Fluorescence and Full-Field Optical Coherence Microscopy for Biomedical Imaging Applications
Author: Auksorius, Egidijus; Bromberg, Yaron; Motiejūnaitė, Rūta; Pieretti, Alberto Christian; Liu, Linbo; Coron, Emmanuel; Aranda, Jorge; Goldstein, Allan Moises; Bouma, Brett; Kazlauskas, Andrius; Tearney, Guillermo James

Note: Order does not necessarily reflect citation order of authors.

Citation: Auksorius, Egidijus, Yaron Bromberg, Rūta Motiejūnaitė, Alberto Pieretti, Linbo Liu, Emmanuel Coron, Jorge Aranda, et al. 2012. Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications. Biomedical Optics Express 3(3): 661-666.
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Abstract: Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate the potential of this dual modality, a fixed and labeled mouse retina was imaged. Results showed that both techniques can provide complementary information and therefore the system could potentially be useful for biomedical imaging applications.
Published Version: doi:10.1364/BOE.3.000661
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296550/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10019005

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