Browsing FAS Scholarly Articles by Title
Now showing items 1359-1378 of 18292
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Biobricks and Crocheted Coral: Dispatches from the Life Sciences in the Age of Fabrication
(Cambridge University Press (CUP), 2013)What does “life” become at a moment when biological inquiry proceeds by manufacturing biological artifacts and systems? In this article, I juxtapose two radically different communities, synthetic biologists and Hyperbolic ... -
A Biochemically Active MCM-like Helicase in Bacillus Cereus
(Oxford University Press, 2009)The mini-chromosome maintenance (MCM) proteins serve as the replicative helicases in archaea and eukaryotes. Interestingly, an MCM homolog was identified, by BLAST analysis, within a phage integrated in the bacterium ... -
A Biocompatible Alkene Hydrogenation Merges Organic Synthesis with Microbial Metabolism
(Wiley-Blackwell, 2014)Organic chemists and metabolic engineers use largely orthogonal technologies to construct essential small molecules like pharmaceuticals and commodity chemicals. While chemists have leveraged the unique capabilities of ... -
The Biodiversity Heritage Library: sharing biodiversity with the world
(Sage, 2009)Ten major natural history museum libraries, botanical libraries, and research institutions in the United Kingdom and the United States joined in 2005 to develop a strategy and operational plan to digitize the published ... -
Bioelectric Signaling Regulates Size in Zebrafish Fins
(Public Library of Science, 2014)The scaling relationship between the size of an appendage or organ and that of the body as a whole is tightly regulated during animal development. If a structure grows at a different rate than the rest of the body, this ... -
Bioelectrical Domain Walls in Homogeneous Tissues
(Springer Science and Business Media LLC, 2020-01-20)Electrical signaling in biology is typically associated with action potentials, transient spikes in membrane voltage that return to baseline. Hodgkin-Huxley and related conductance-based models of electrophysiology belong ... -
A bioelectrical phase transition patterns the first vertebrate heartbeats
(Springer Science and Business Media LLC, 2023-09-27)A regular heartbeat is essential to vertebrate life. In the mature heart this function is driven by an anatomically localized pacemaker. In contrast, pacemaking capability is broadly distributed in the early embryonic ... -
Bioequivalence: The Regulatory Career of a Pharmaceutical Concept
(Johns Hopkins University Press, 2011)Generic drugs cannot be marketed without regulatory and clinical demonstration of "bioequivalence." The authors argue that the concept of "bioequivalence" is a joint regulatory and scientific creation, not purely a technical ... -
Bioethics: Using Its Historical and Social Context
(Little Brown and Company, 2001) -
Biofilm attachment reduction on bioinspired, dynamic, micro-wrinkling surfaces
(IOP Publishing, 2013-09-27)Most bacteria live in multicellular communities known as biofilms that are adherent to surfaces in our environment, from sea beds to plumbing systems. Biofilms are often associated with clinical infections, nosocomial ... -
Biofilm attachment reduction on bioinspired, dynamic, micro-wrinkling surfaces
(IOP Publishing, 2013)Most bacteria live in multicellular communities known as biofilms that are adherent to surfaces in our environment, from sea beds to plumbing systems. Biofilms are often associated with clinical infections, nosocomial ... -
Biogenic Versus Anthropogenic Sources of CO in the United States
(American Geophysical Union, 2008)Aircraft observations of carbon monoxide (CO) from the ICARTT campaign over the eastern United States in summer 2004 (July 1–August 15), interpreted with a global 3-D model of tropospheric chemistry (GEOS-Chem), show that ... -
Biogeochemical drivers of the fate of riverine mercury discharged to the global and Arctic oceans
(Wiley-Blackwell, 2015)Rivers discharge 28 ± 13 Mmol yr1 of mercury (Hg) to ocean margins, an amount comparable to atmospheric deposition to the global oceans. Most of the Hg discharged by rivers is sequestered by burial of benthic sediment in ... -
Biogeography in a Continental Island: Population Structure of the Relict Endemic Centipede Craterostigmus tasmanianus (Chilopoda, Craterostigmomorpha) in Tasmania Using 16S rRNA and COI
(Oxford University Press (OUP), 2011)We used 16S ribosomal RNA (rRNA) and cytochrome c oxidase subunit I (COI) sequence data to investigate the population structure in the centipede Craterostigmus tasmanianus Pocock, 1902 (Chilopoda: Craterostigmomorpha: ... -
Bioinspiration: something for everyone
(The Royal Society, 2015)‘Bioinspiration’—using phenomena in biology to stimulate research in non-biological science and technology—is a strategy that suggests new areas for research. Beyond its potential to nucleate new ideas, bioinspiration has ... -
Bioinspired Artificial Melanosomes As Colorimetric Indicators of Oxygen Exposure
(American Chemical Society (ACS), 2016-02-15)Many industries require irreversibly responsive materials for use as sensors or detectors of environmental exposure. We describe the synthesis and fabrication of a nontoxic surface coating that reports oxygen exposure of ... -
Bioinspired kirigami metasurfaces as assistive shoe grips
(Springer Science and Business Media LLC, 2020-06-01)Falls and subsequent complications are major contributors to morbidity and mortality, especially in older adults. Here, by taking inspiration from claws and scales found in nature, we show that buckling kirigami structures ... -
Bioinspired micrograting arrays mimicking the reverse color diffraction elements evolved by the butterfly Pierella luna
(Proceedings of the National Academy of Sciences, 2014)Recently, diffraction elements that reverse the color sequence normally observed in planar diffraction gratings have been found in the wing scales of the butterfly Pierella luna. Here, we describe the creation of an ... -
Bioinspired neuron-like electronics
(Springer Nature, 2019-02-25)As an important application of functional biomaterials, neural probes have contributed substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be applied to the development of neural probes, ... -
A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling
(Nature Publishing Group, 2014)Thrombosis and biofouling of extracorporeal circuits and indwelling medical devices cause significant morbidity and mortality worldwide. We describe a bioinspired coating that repels blood from virtually any material by ...