Now showing items 3684-3703 of 18256

    • Development of potent in vivo mutagenesis plasmids with broad mutational spectra 

      Badran, Ahmed H.; Liu, David R. (Nature Pub. Group, 2015)
      Methods to enhance random mutagenesis in cells offer advantages over in vitro mutagenesis, but current in vivo methods suffer from a lack of control, genomic instability, low efficiency and narrow mutational spectra. Using ...
    • The Development of Reasoning About Beliefs: Fact, Preference, and Ideology 

      Heiphetz, Larisa Alexandra; Spelke, Elizabeth S.; Harris, Paul Lansley; Banaji, Mahzarin R. (Elsevier BV, 2013)
      The beliefs people hold about the social and physical world are central to self-definition and social interaction. The current research analyzes reasoning about three kinds of beliefs: those that concern matters of fact ...
    • Development of Sensitivity to Geometry in Visual Forms 

      Izard, Véronique; Spelke, Elizabeth S. (Springer Verlag, 2009)
      Geometric form perception has been extensively studied in human children, but it has not been systematically characterized from the perspective of formal geometry. Here, we present the findings of three experiments that ...
    • The Development of Sex Differences in Digital Formula from Infancy in the Fels Longitudinal Study 

      McIntyre, Matthew H.; Ellison, Peter T.; Lieberman, Daniel Eric; Demerath, Ellen; Towne, Bradford (Royal Society, The, 2005)
      Relative finger lengths, especially the second-to-fourth finger length ratio, have been proposed as useful markers for prenatal testosterone action. This claim partly depends on an association of relative finger lengths ...
    • Development of the Corticospinal and Callosal Tracts from Extremely Premature Birth up to 2 Years of Age 

      Braga, Rodrigo M.; Roze, Elise; Ball, Gareth; Merchant, Nazakat; Tusor, Nora; Arichi, Tomoki; Edwards, David; Rueckert, Daniel; Counsell, Serena J. (Public Library of Science, 2015)
      White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magnetic resonance imaging. The aims of this study were i. to generate dynamic population-averaged white ...
    • Development of the first-mention bias 

      Hartshorne, Joshua; Snedeker, Jesse; Nappa, Rebecca (Cambridge University Press (CUP), 2014)
      In many contexts, pronouns are interpreted as referring to the character mentioned first in the previous sentence, an effect called the ‘first-mention bias’. While adults can rapidly use the first-mention bias to guide ...
    • Development, specification, and diversity of callosal projection neurons 

      Fame, Ryann M.; MacDonald, Jessica Linn; Macklis, Jeffrey Daniel (Elsevier, 2011)
      Callosal projection neurons (CPN) are a diverse population of neocortical projection neurons that connect the two hemispheres of the cerebral cortex via the corpus callosum. They play key roles in high-level associative ...
    • Developmental Basis of an Anatomical Novelty: Heteroarthrocarpy in Cakile Lanceolata and Erucaria Erucarioides (Brassicaceae) 

      Hall, Jocelyn C.; Tisdale, Tracy E.; Donohue, Kathleen; Kramer, Elena (University of Chicago Press, 2006)
      To understand the developmental basis of a novel anatomical feature, we present a comparative developmental study of an ecologically significant novelty in fruit morphology. Most members of the tribe Brassiceae have ...
    • Developmental Bias in Cleavage-Stage Mouse Blastomeres 

      Tabansky, Inna; Lenarcic, Alan; Draft, Ryan Wesley; Loulier, Karine; Keskin, Derin Benerci; Rosains, Jacqueline; Rivera-Feliciano, Jose; Lichtman, Jeff; Livet, Jean; Stern, Joel N H; Sanes, Joshua R.; Eggan, Kevin Carl (Elsevier BV, 2013)
      BACKGROUND: The cleavage-stage mouse embryo is composed of superficially equivalent blastomeres that will generate both the embryonic inner cell mass (ICM) and the supportive trophectoderm (TE). However, it remains unsettled ...
    • Developmental Changes in the Representation of Faces 

      Diamond, R; Carey, Susan E. (Elsevier BV, 1977)
      Children from age 6 to 16 judged which of two photographs of unfamiliar faces showed the same person as an inspection photograph. Recognition accuracy improved markedly between ages 6 and 10 with little change thereafter. ...
    • Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice 

      Sohur, Usharbudh Shivraj; Arlotta, Paola; Macklis, Jeffrey Daniel (Frontiers Research Foundation, 2012)
      Whether induction of low-level neurogenesis in normally non-neurogenic regions of the adult brain mimics aspects of developmental neurogenesis is currently unknown. Previously, we and others identified that biophysically ...
    • Developmental Gene Discovery in a Hemimetabolous Insect: De Novo Assembly and Annotation of a Transcriptome for the Cricket Gryllus Bimaculatus 

      Zeng, Victor; Ewen-Campen, Benjamin Scott; Horch, Hadley W.; Roth, Siegfried; Mito, Taro; Extavour, Cassandra G. (Public Library of Science, 2013-04-05)
      Most genomic resources available for insects represent the Holometabola, which are insects that undergo complete metamorphosis like beetles and flies. In contrast, the Hemimetabola (direct developing insects), representing ...
    • Developmental mechanism of the periodic membrane skeleton in axons 

      Zhong, Guisheng; He, Jiang; Zhou, Ruobo; Lorenzo, Damaris; Babcock, Hazen P; Bennett, Vann; Zhuang, Xiaowei (eLife Sciences Publications, Ltd, 2014)
      Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown. Here, we studied the developmental ...
    • Developmental mechanisms of stripe patterns in rodents 

      Mallarino, Ricardo; Henegar, Corneliu; Mirasierra, Mercedes; Manceau, Marie; Schradin, Carsten; Vallejo, Mario; Beronja, Slobodan; Barsh, Gregory S.; Hoekstra, Hopi E. (Springer Nature, 2016)
      Mammalian color patterns are among the most recognizable characters found in nature and can have a profound impact on fitness. However, little is known about the mechanisms underlying their formation and subsequent evolution. ...
    • Developmental origins of the world's largest flowers, Rafflesiaceae 

      Nikolov, L. A.; Endress, P. K.; Sugumaran, M.; Sasirat, S.; Vessabutr, S.; Kramer, Elena M.; Davis, Charles Cavender (Proceedings of the National Academy of Sciences, 2013)
      Rafflesiaceae, which produce the world’s largest flowers, have captivated the attention of biologists for nearly two centuries. Despite their fame, however, the developmental nature of the floral organs in these giants has ...
    • Developmental Plasticity in a Biocultural Context 

      Ellison, Peter (John Wiley & Sons, Ltd., 2009)
    • Developmental regulation of myeloerythroid progenitor function by the Lin28b–let-7–Hmga2 axis 

      Rowe, R. Grant; Wang, Leo D.; Coma, Silvia; Han, Areum; Mathieu, Ronald; Pearson, Daniel S.; Ross, Samantha; Sousa, Patricia; Nguyen, Phi T.; Rodriguez, Antony; Wagers, Amy J.; Daley, George Q. (The Rockefeller University Press, 2016)
      For appropriate development, tissue and organ system morphogenesis and maturation must occur in synchrony with the overall developmental requirements of the host. Mistiming of such developmental events often results in ...
    • The Developmental Role of Agouti in Color Pattern Evolution 

      Manceau, Marie; Domingues, Vera S.; Mallarino, Ricardo; Hoekstra, Hopi E. (American Association for the Advancement of Science (AAAS), 2011)
      Animal color patterns can affect fitness in the wild; however, little is known about the mechanisms that control their formation and subsequent evolution. We took advantage of two locally camouflaged populations of Peromyscus ...
    • A Developmental Staging Series for the Lizard Genus Anolis: A New System for the Integration of Evolution, Development, and Ecology 

      Sanger, Thomas J.; Losos, Jonathan; Gibson-Brown, Jeremy J. (John Wiley & Sons, 2008)
      Vertebrate developmental biologists typically rely on a limited number of model organisms to understand the evolutionary bases of morphological change. Unfortunately, a typical model system for squamates (lizards and snakes) ...
    • Developmental variation of the primate dentition: The 2011 AAPA symposium in honor of Don Reid 

      Smith, Tanya; Guatelli-Steinberg, Debbie (Wiley-Blackwell, 2011)