Browsing FAS Scholarly Articles by Title
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Early Developmental Exposure to dsRNA Is Critical for Initiating Efficient Nuclear RNAi in C. elegans
(Elsevier BV, 2017)RNAi has enabled researchers to study the function of many genes. However, it is not understood why some RNAi experiments succeed while others do not. Here, we show in C. elegans that pharyngeal muscle is resistant to RNAi ... -
The Early Evolution of Eukaryotes: A Geological Perspective
(American Association for the Advancement of Science, 1992)Molecular phylogenies of eukaryotic organisms imply patterns of biological and environmental history that can be tested against the geological record. As predicted by sequence comparisons, Precambrian rocks show evidence ... -
Early Formation and Late Merging of the Giant Galaxies
(American Astronomical Society, 2004)The most luminous galaxies in the present universe are found at the centers of the most massive dark matter halos: rich galaxy clusters. In the LambdaCDM cosmology, such massive halo cores are present at redshift z = 6 ... -
Early Holocene Openlands in Southern New England
(Ecological Society of America, 2006)The pre-historical vegetation structure in temperate forest regions is much debated among European and North American ecologists and conservationists. Frans Vera’s recent hypothesis that large mammals created mosaics of ... -
Early Life Nutrition Modulates Muscle Stem Cell Number: Implications for Muscle Mass and Repair
(Mary Ann Liebert, 2011)Suboptimal nutrition during prenatal and early postnatal development is associated with increased risk for type 2 diabetes during adult life. A hallmark of such diabetes risk is altered body composition, including reduced ... -
Early Lineage Priming by Trisomy of Erg Leads to Myeloproliferation in a Down Syndrome Model
(Public Library of Science, 2015)Down syndrome (DS), with trisomy of chromosome 21 (HSA21), is the commonest human aneuploidy. Pre-leukemic myeloproliferative changes in DS foetal livers precede the acquisition of GATA1 mutations, transient myeloproliferative ... -
Early Marriage, Age of Menarche, and Female Schooling Attainment in Bangladesh
(University of Chicago Press, 2008)Using data from rural Bangladesh, we explore the hypothesis that women attain less schooling as a result of social and financial pressure to marry young. We isolate the causal effect of marriage timing using age of menarche ... -
Early Mesopotamian Urbanism: A New View from the North
(Antiquity Publications, 2007)For many years, the southern Mesopotamia of Ur and Uruk, ancient Sumer, has been seen as the origin centre of civilisation and cities: ‘The urban implosion of late-fourth- and early-third-millennium Mesopotamia resulted ... -
Early Modern Floral: The Agency of Ornament in Ottoman and Safavid Visual Cultures
(Princeton University Press, 2016) -
An Early Modernist’s Perspective
(University of Chicago Press, 2004)Historians of science can gain new insights into the material practices and intellectual trajectories of natural philosophers by attending to evidence of what they read and how. From the time of the early modern period we ... -
Early Neoproterozoic Basin Formation in Yukon, Canada: Implications for the Make-Up and Break-Up of Rodinia
(Geological Association of Canada, 2012)Geological mapping and stratigraphic anaylsis of the early Neoproterozoic Fifteenmile Group in the western Ogilvie Mountains of Yukon, Canada, has revealed large lateral facies changes in both carbonate and siliciclastic ... -
Early Neoproterozoic scale microfossils in the Lower Tindir Group of Alaska and the Yukon Territory
(Geological Society of America, 2010)The Tindir Group is a <4-km-thick Neoproterozoic succession exposed in the Tatonduk inlier of east-central Alaska and the western Yukon Territory. The Tindir Group is informally divided into the Lower Tindir Group, which ... -
Early Onset Alcohol Use and Self-Harm: A Discordant Twin Analysis
(Wiley-Blackwell, 2015)Background Self-harm has considerable societal and economic costs and has been extensively studied in relation to alcohol involvement. Whereas early onset alcohol use (EAU) has been causally linked to maladaptive clinical ... -
Early Photosynthetic Eukaryotes Inhabited Low-Salinity Habitats
(Proceedings of the National Academy of Sciences, 2017-08-14)The early evolutionary history of the chloroplast lineage remains an open question. It is widely accepted that the endosymbiosis that established the chloroplast lineage in eukaryotes can be traced back to a single event, ... -
Early Pleistocene Glacial Cycles and the Integrated Summer Insolation Forcing
(American Association for the Advancement of Science, 2006)Long-term variations in Northern Hemisphere summer insolation are generally thought to control glaciation. But the intensity of summer insolation is primarily controlled by 20,000-year cycles in the precession of the ... -
Early Social Cognition in Three Cultural Contexts
(Wiley-Blackwell, 2011)The influence of culture on cognitive development is well established for school age and older children. But almost nothing is known about how different parenting and socialization practices in different cultures affect ... -
Early Structure Formation and Reionization in a Cosmological Model with a Running Primordial Power Spectrum
(American Astronomical Society, 2003)We study high-redshift structure formation and reionization in a LambdaCDM universe under the assumption that the spectral power index of primordial density fluctuations is a function of length scale. We adopt a particular ... -
Early Structure Formation and Reionization in a Warm Dark Matter Cosmology
(American Astronomical Society, 2003)We study the first structure formations in Lambda-dominated universes using large cosmological N-body/smoothed particle hydrodynamics simulations. We consider a standard Lambda cold dark matter (CDM) model and a Lambda ... -
Early Ultraviolet, Optical, and X‐Ray Observations of the Type IIP SN 2005cs in M51 with Swift
(American Astronomical Society, 2007)