Browsing FAS Scholarly Articles by Title
Now showing items 5946-5965 of 18292
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Fitness Trade-Offs in the Evolution of Dihydrofolate Reductase and Drug Resistance in Plasmodium falciparum
(Public Library of Science, 2011)Background: Patterns of emerging drug resistance reflect the underlying adaptive landscapes for specific drugs. In Plasmodium falciparum, the parasite that causes the most serious form of malaria, antifolate drugs inhibit ... -
Fitness Variation Due To Sexual Antagonism and Linkage Disequilibrium
(Wiley-Blackwell, 2010)Extensive fitness variation for sexually antagonistic characters has been detected in nature. However, current population genetic theory suggests that sexual antagonism is unlikely to play a major role in the maintenance ... -
Fitting Formula for Flux Scintillation of Compact Radio Sources
(American Astronomical Society, 2005)We present a fitting function to describe the statistics of flux modulations caused by interstellar scintillation. The function models a very general quantity: the cross-correlation of the flux observed from a compact radio ... -
Fitting the Mind to the World: Face Adaptation and Attractiveness Aftereffects
(Blackwell Publishers, 2003)Average faces are attractive, but what is average depends on experience. We examined the effect of brief exposure to consistent facial distortions on what looks normal (average) and what looks attractive. Adaptation to a ... -
Five AI Challenges in Strategyproof Computing
(2003)Computational systems are now distributed by default, and designed, owned and used by multiple self-interested parties. In the face of this growing system complexity, we need a unifying design paradigm, that supports ... -
Five Harlem Short Stories by Zora Neale Hurston
(Universitätsverlag WINTER Gmbh, 2010) -
Five hundred microsatellite loci for Peromyscus
(Springer Science + Business Media, 2010)Mice of the genus Peromyscus, including several endangered subspecies, occur throughout North America and have been important models for conservation research. We describe 526 primer pairs that amplify microsatellite DNA ... -
Five Problems in Quantum Gravity
(Elsevier, 2009)We present five open problems in quantum gravity which one might reasonably hope to solve in the next decade. Hints appearing in the literature are summarized for each one. -
Fixation Probabilities for Any Configuration of Two Strategies on Regular Graphs
(Nature Publishing Group, 2016)Population structure and spatial heterogeneity are integral components of evolutionary dynamics, in general, and of evolution of cooperation, in particular. Structure can promote the emergence of cooperation in some ... -
Fixed Energy Universality for Generalized Wigner Matrices
(Wiley-Blackwell, 2015)We prove the Wigner-Dyson-Mehta conjecture at fixed energy in the bulk of the spectrum for generalized symmetric and Hermitian Wigner matrices. Previous results concerning the universality of random matrices either require ... -
Fixed single-cell transcriptomic characterization of human radial glial diversity
(2016)The human neocortex is created from diverse intermixed progenitors in the prenatal germinal zones. These progenitors have been difficult to characterize since progenitors—particularly radial glia (RG)—are rare, and are ... -
Fixing All Moduli in a Simple F-theory Compactification
(International Press, 2005)We discuss a simple example of an F-theory compactification on a Calabi-Yau fourfold where background fluxes, nonperturbative effects from Euclidean D3 instantons and gauge dynamics on D7 branes allow us to fix all closed ... -
FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions
(American Society for Biochemistry and Molecular Biology, 2000)The FKBP12-rapamycin associated protein (FRAP, also RAFT, mTOR) belongs to a family of phosphatidylinositol kinase-related kinases, These kinases mediate cellular responses to stresses such as DNA damage and nutrient ... -
FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction
(National Academy of Sciences, 2002)FKBP12-rapamycin associated protein (FRAP, also known as mTOR or RAFT) is the founding member of the phosphatidylinositol kinase-related kinase family and functions as a sensor of physiological signals that regulate cell ... -
Flagellar dynamics of a connected chain of active, polar, Brownian particles
(The Royal Society, 2013)We show that active, self-propelled particles that are connected together to form a single chain that is anchored at one end can produce the graceful beating motions of flagella. Changing the boundary condition from a clamp ... -
The flagellar motor of Caulobacter crescentus generates more torque when a cell swims backward
(2016)Caulobacter crescentus, a monotrichous bacterium, swims by rotating a single right-handed helical filament. CW motor rotation thrusts the cell forward 1, a mode of motility known as the pusher mode; CCW motor rotation pulls ... -
The flare activity of Sagittarius A*
(EDP Sciences, 2006)Context. We report new simultaneous near-infrared/sub-millimeter/X-ray observations of the SgrA* counterpart associated with the massive 3–4×106M⊙ black hole at the Galactic Center. Aims. The main aim is to investigate the ... -
Flash Caching on the Storage Client
(USENIX Association, 2013)Flash memory has recently become popular as a caching medium. Most uses to date are on the storage server side. We investigate a different structure: flash as a cache on the client side of a networked storage environment. ... -
Flash Force: A Visual History of Might, Right and Light
(Association of Neuroesthetics, Berlin, 2011) -
Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin
(American Chemical Society, 2014)We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin ...