Now showing items 640-659 of 18292

    • Ancient human genomes suggest three ancestral populations for present-day Europeans 

      Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Kirsanow, Karola; Sudmant, Peter H.; Schraiber, Joshua G.; Castellano, Sergi; Lipson, Mark; Berger, Bonnie; Economou, Christos; Bollongino, Ruth; Fu, Qiaomei; Bos, Kirsten I.; Nordenfelt, Susanne; Li, Heng; de Filippo, Cesare; Prüfer, Kay; Sawyer, Susanna; Posth, Cosimo; Haak, Wolfgang; Hallgren, Fredrik; Fornander, Elin; Rohland, Nadin; Delsate, Dominique; Francken, Michael; Guinet, Jean-Michel; Wahl, Joachim; Ayodo, George; Babiker, Hamza A.; Bailliet, Graciela; Balanovska, Elena; Balanovsky, Oleg; Barrantes, Ramiro; Bedoya, Gabriel; Ben-Ami, Haim; Bene, Judit; Berrada, Fouad; Bravi, Claudio M.; Brisighelli, Francesca; Busby, George B. J.; Cali, Francesco; Churnosov, Mikhail; Cole, David E. C.; Corach, Daniel; Damba, Larissa; van Driem, George; Dryomov, Stanislav; Dugoujon, Jean-Michel; Fedorova, Sardana A.; Romero, Irene Gallego; Gubina, Marina; Hammer, Michael; Henn, Brenna M.; Hervig, Tor; Hodoglugil, Ugur; Jha, Aashish R.; Karachanak-Yankova, Sena; Khusainova, Rita; Khusnutdinova, Elza; Kittles, Rick; Kivisild, Toomas; Klitz, William; Kučinskas, Vaidutis; Kushniarevich, Alena; Laredj, Leila; Litvinov, Sergey; Loukidis, Theologos; Mahley, Robert W.; Melegh, Béla; Metspalu, Ene; Molina, Julio; Mountain, Joanna; Näkkäläjärvi, Klemetti; Nesheva, Desislava; Nyambo, Thomas; Osipova, Ludmila; Parik, Jüri; Platonov, Fedor; Posukh, Olga; Romano, Valentino; Rothhammer, Francisco; Rudan, Igor; Ruizbakiev, Ruslan; Sahakyan, Hovhannes; Sajantila, Antti; Salas, Antonio; Starikovskaya, Elena B.; Tarekegn, Ayele; Toncheva, Draga; Turdikulova, Shahlo; Uktveryte, Ingrida; Utevska, Olga; Vasquez, René; Villena, Mercedes; Voevoda, Mikhail; Winkler, Cheryl; Yepiskoposyan, Levon; Zalloua, Pierre; Zemunik, Tatijana; Cooper, Alan; Capelli, Cristian; Thomas, Mark G.; Ruiz-Linares, Andres; Tishkoff, Sarah A.; Singh, Lalji; Thangaraj, Kumarasamy; Villems, Richard; Comas, David; Sukernik, Rem; Metspalu, Mait; Meyer, Matthias; Eichler, Evan E.; Burger, Joachim; Slatkin, Montgomery; Pääbo, Svante; Kelso, Janet; Reich, David; Krause, Johannes (2014)
      We sequenced the genomes of a ~7,000 year old farmer from Germany and eight ~8,000 year old hunter-gatherers from Luxembourg and Sweden. We analyzed these and other ancient genomes1–4 with 2,345 contemporary humans to show ...
    • Ancient Impact and Aqueous Processes at Endeavour Crater, Mars 

      Knoll, Andrew Herbert; Squyres, S. W.; Arvidson, R. E.; Bell, J. F., III; Calef, F., III; Clark, B. C.; Cohen, B. A.; Crumpler, L. A.; de Souza, P. A., Jr.; Farrand, W. H.; Gellert, R.; Grant, J.; Hurowitz, J. A.; Herkenhoff, K. E.; Johnson, J. R.; Jolliff, B. L.; Li, R.; McLennan, S. M.; Ming, D. W.; Mittlefehldt, D. W.; Parker, T. J.; Paulsen, G.; Rice, M. S.; Ruff, S. W.; Schröder, C.; Yen, A. S.; Zacny, K. (American Association for the Advancement of Science, 2012)
      The rover Opportunity has investigated the rim of Endeavour Crater, a large ancient impact crater on Mars. Basaltic breccias produced by the impact form the rim deposits, with stratigraphy similar to that observed at ...
    • Ancient origin of placental expression in the growth hormone genes of anthropoid primates 

      Papper, Z.; Jameson, N. M.; Romero, R.; Weckle, A. L.; Mittal, P.; Benirschke, K.; Santolaya-Forgas, J.; Uddin, M.; Haig, David Addison; Goodman, M.; Wildman, D. E. (Proceedings of the National Academy of Sciences, 2009)
      In anthropoid primates, growth hormone (GH) genes have undergone at least 2 independent locus expansions, one in platyrrhines (New World monkeys) and another in catarrhines (Old World monkeys and apes). In catarrhines, the ...
    • Ancient West African Foragers in the Context of African Population History 

      Lipson, Mark; Rohland-Pinello, Nadin; Lawson, Ann; Lavachery, Philippe; Mindzie, Christophe Mbida; Orban, Rosine; Semal, Patrick; Van Neer, Wim; Veeramah, Krishna R.; Kennett, Douglas J.; Patterson, Nick; Hellenthal, Garrett; Lalueza-Fox, Carles; MacEachern, Scott; Prendergast, Mary E.; Reich, David; Ribot, Isabelle; Mallick, Swapan; Olalde, Inigo; Adamski, Nicole; Broomandkhoshbacht, Nadin; López, Saloa; Oppenheimer, Jonas; Stewardson, Kristin; Asombang, Raymond; Bocherens, Herve; Bradman, Neil; Culleton, Brendan; Cornelissen, Els; Crevecoeur, Isabelle; de Maret, Pierre; Fomine, Forka Leypey Mathew; Sawchuk, Elizabeth; Thomas, Mark (Springer Science and Business Media LLC, 2020-01)
      We generated genome-wide DNA data from four children buried roughly 8000 and 3000 years ago at Shum Laka (Cameroon), one of the earliest archaeological sites within the probable homeland of Bantu languages. One individual ...
    • And Heal the Sick: The Hospital and the Patient in the 19th Century America 

      Rosenberg, Charles (Carnegie Mellon University Press, 1977)
    • Andean Growth and the Deceleration of South American Subduction: Time Evolution of a Coupled Orogen-subduction System 

      Meade, Brendan J.; Conrad, Clinton P. (Elsevier, 2008)
      Present-day orography at the Andean margin is a result of isostasy, tectonic accretion, and erosional processes. The resulting excess mass of the Andes gives rise to frictional stresses on the seismogenic plate interface ...
    • Androgen Exposure and Sensation-Seeking in Young Males 

      Campbell, Bruce C.; Gray, Peter B.; Dreber, Anna; Apicella, Carmel; Little, A.; Ellison, Peter (John Wiley & Sons, 2008)
      Testosterone is thought to be associated with short attention spans, increased novelty, and thrill seeking and behavioral disinhibition in men. However, there is little empirical evidence for such associations among normal ...
    • Androgen Receptor CAG Repeats and Body Composition Among Ariaal Men 

      Campbell, Benjamin C.; Gray, Peter B.; Eisenberg, Dan T. A.; Ellison, Peter; Sorenson, Michael D. (Blackwell Publishing, 2007)
      To determine the population variation in the androgen receptor (AR) and its association with body composition in a subsistence population, we sampled 87 settled and 65 nomadic males ages 20+ among the Ariaal of northern ...
    • Anelasticity across seismic to tidal timescales: a self-consistent approach 

      Lau, Harriet C. P.; Faul, Ulrich; Mitrovica, Jerry; Al-Attar, David; Tromp, Jeroen; Garapić, Gordana (Oxford University Press, 2017)
    • Anemia at the Initiation of Tuberculosis Therapy Is Associated with Delayed Sputum Conversion among Pulmonary Tuberculosis Patients in Dar-es-Salaam, Tanzania 

      Nagu, Tumaini J.; Spiegelman, Donna; Hertzmark, Ellen; Aboud, Said; Makani, Julie; Matee, Mecky I.; Fawzi, Wafaie; Mugusi, Ferdinand (Public Library of Science, 2014)
      Background: Pulmonary tuberculosis and anemia are both prevalent in Tanzania. There is limited and inconsistent literature on the association between anemia and sputum conversion following tuberculosis treatment. Methods: ...
    • Aneuploidy Prediction and Tumor Classification with Heterogeneous Hidden Conditional Random Fields 

      Barutcuoglu, Zafer; Airoldi, Edoardo; Dumeaux, Vanessa; Schapire, Robert E.; Troyanskaya, Olga G. (Oxford University Press, 2008)
      Motivation: The heterogeneity of cancer cannot always be recognized by tumor morphology, but may be reflected by the underlying genetic aberrations. Array-CGH methods provide highthroughput data on genetic copy numbers, ...
    • Angels and demons in the pages of Lebor na hUidre 

      McKenna, Catherine (Colgate University Press, 2011)
    • Angiopoietin-1 Requires p190 RhoGAP to Protect against Vascular Leakage in Vivo 

      Mammoto, Tadanori; Parikh, Samir M.; Mammoto, Akiko; Gallagher, Diana; Chan, Barden; Mostoslavsky, Gustavo; Ingber, Donald E.; Sukhatme, Vikas P. (American Society for Biochemistry and Molecular Biology, 2007)
    • Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling 

      Lin, Michelle I; Price, Emily N; Boatman, Sonja; Hagedorn, Elliott J; Trompouki, Eirini; Satishchandran, Sruthi; Carspecken, Charles W; Uong, Audrey; DiBiase, Anthony; Yang, Song; Canver, Matthew C; Dahlberg, Ann; Lu, Zhigang; Zhang, Cheng Cheng; Orkin, Stuart H; Bernstein, Irwin D; Aster, Jon C; White, Richard M; Zon, Leonard I (eLife Sciences Publications, Ltd, 2015)
      Angiopoietin-like proteins (angptls) are capable of ex vivo expansion of mouse and human hematopoietic stem and progenitor cells (HSPCs). Despite this intriguing ability, their mechanism is unknown. In this study, we show ...
    • Angiotensin II Induced Cardiac Dysfunction on a Chip 

      Horton, Renita E.; Yadid, Moran; McCain, Megan L.; Sheehy, Sean P.; Pasqualini, Francesco S.; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit (Public Library of Science, 2016)
      In vitro disease models offer the ability to study specific systemic features in isolation to better understand underlying mechanisms that lead to dysfunction. Here, we present a cardiac dysfunction model using angiotensin ...
    • Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels 

      Chauhan, Vikash P.; Martin, John D.; Liu, Hao; Lacorre, Delphine A.; Jain, Saloni R.; Kozin, Sergey V.; Stylianopoulos, Triantafyllos; Mousa, Ahmed S.; Han, Xiaoxing; Adstamongkonkul, Pichet; Popović, Zoran; Huang, Peigen; Bawendi, Moungi G.; Boucher, Yves; Jain, Rakesh K. (Nature Pub. Group, 2013)
      Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan ...
    • Angular Emission Characteristics of Quantum Cascade Spiral Microlasers 

      Hentschel, Martina; Belkin, Mikhail A.; Audet, Ross; Capasso, Federico (Optical Society of America, 2009)
      We perform ray and wave simulations of passive and active spiral-shaped optical microcavities, comparing our results to experimental data obtained with mid-infrared quantum cascade spiral microlasers. Focusing on the ...
    • Angular Fluctuations of a Multicomponent Order Describe the Pseudogap of \(YBa_2Cu_3O_{6+x}\) 

      Hayward, Lauren; Hawthorn, David G.; Melko, Roger G.; Sachdev, Subir (American Association for the Advancement of Science (AAAS), 2014)
      The hole-doped cuprate high-temperature superconductors enter the pseudogap regime as their superconducting critical temperature, \(T_c\), falls with decreasing hole density. Recent x-ray scattering experiments in ...
    • Angular Momentum in Disk Wind Revealed in the Young Star MWC 349A 

      Zhang, Qizhou; Claus, Brian; Watson, Linda; Moran, James (American Astronomical Society, 2017)
      Disk winds are thought to play a critical role in star birth. As winds extract excess angular momentum from accretion disks, matter in the disk can be transported inward to the star to fuel mass growth. However, the ...