Browsing FAS Scholarly Articles by Keyword "Effective Population Size"

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    • Genetic Diversity in the Interference Selection Limit 

      Good, Benjamin H.; Walczak, Aleksandra M.; Neher, Richard A.; Desai, Michael M. (Public Library of Science, 2014)
      Pervasive natural selection can strongly influence observed patterns of genetic variation, but these effects remain poorly understood when multiple selected variants segregate in nearby regions of the genome. Classical ...

    • Loss and Recovery of Genetic Diversity in Adapting Populations of HIV 

      Pennings, Pleuni S.; Kryazhimskiy, Sergey; Wakeley, John (Public Library of Science, 2014)
      The evolution of drug resistance in HIV occurs by the fixation of specific, well-known, drug-resistance mutations, but the underlying population genetic processes are not well understood. By analyzing within-patient ...