Browsing FAS Scholarly Articles by Keyword "Electrophysiology"

Now showing items 1-4 of 4

    • Angiotensin II Induced Cardiac Dysfunction on a Chip 

      Horton, Renita E.; Yadid, Moran; McCain, Megan L.; Sheehy, Sean P.; Pasqualini, Francesco S.; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit (Public Library of Science, 2016)
      In vitro disease models offer the ability to study specific systemic features in isolation to better understand underlying mechanisms that lead to dysfunction. Here, we present a cardiac dysfunction model using angiotensin ...

    • Bioelectric Signaling Regulates Size in Zebrafish Fins 

      Perathoner, Simon; Daane, Jacob M.; Henrion, Ulrike; Seebohm, Guiscard; Higdon, Charles W.; Johnson, Stephen L.; Nüsslein-Volhard, Christiane; Harris, Matthew P. (Public Library of Science, 2014)
      The scaling relationship between the size of an appendage or organ and that of the body as a whole is tightly regulated during animal development. If a structure grows at a different rate than the rest of the body, this ...

    • A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays 

      Patel, Asha K.; Celiz, Adam D.; Rajamohan, Divya; Anderson, Daniel G.; Langer, Robert; Davies, Martyn C.; Alexander, Morgan R.; Denning, Chris (2016)
      Cardiomyocytes from human stem cells have applications in regenerative medicine and can provide models for heart disease and toxicity screening. Soluble components of the culture system such as growth factors within serum ...

    • Improved Tools for the Brainbow Toolbox 

      Cai, Dawen; Cohen, Kimberly B; Luo, Tuanlian; Lichtman, Jeff; Sanes, Joshua R. (Nature Publishing Group, 2013)
      In the transgenic multicolor labeling strategy called 'Brainbow', Cre-loxP recombination is used to create a stochastic choice of expression among fluorescent proteins, resulting in the indelible marking of mouse neurons ...