Browsing FAS Scholarly Articles by Keyword "Engineering"

Now showing items 1-10 of 10

    • The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum 

      Harcombe, William R.; Delaney, Nigel F.; Leiby, Nicholas; Klitgord, Niels; Marx, Christopher J. (Public Library of Science, 2013)
      The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model. It hypothesizes selection upon a proposed optimality criterion in order to predict the set of ...

    • Controlling Interneuron Activity in Caenorhabditis Elegans to Evoke Chemotactic Behaviour 

      Kocabas, Askin; Shen, Ching-Han; Guo, Zengcai V.; Ramanathan, Sharad (Nature Publishing Group, 2012)
      Animals locate and track chemoattractive gradients in the environment to find food. With its small nervous system, Caenorhabditis elegans is a good model system in which to understand how the dynamics of neural activity ...

    • Device fabrication: Three-dimensional printed electronics 

      Lewis, Jennifer; Ahn, Bok Yeop (Nature Publishing Group, 2015)

    • FRAP Analysis: Accounting for Bleaching during Image Capture 

      Wu, Jun; Shekhar, Nandini; Lele, Pushkar Prakash; Lele, Tanmay P. (Public Library of Science, 2012)
      The analysis of Fluorescence Recovery After Photobleaching (FRAP) experiments involves mathematical modeling of the fluorescence recovery process. An important feature of FRAP experiments that tends to be ignored in the ...

    • Molecular Threading: Mechanical Extraction, Stretching and Placement of DNA Molecules from a Liquid-Air Interface 

      Payne, Andrew C.; Andregg, Michael; Kemmish, Kent; Hamalainen, Mark; Bowell, Charlotte; Bleloch, Andrew; Klejwa, Nathan; Lehrach, Wolfgang; Schatz, Ken; Stark, Heather; Marblestone, Adam; Church, George; Own, Christopher S.; Andregg, William (Public Library of Science, 2013)
      We present “molecular threading”, a surface independent tip-based method for stretching and depositing single and double-stranded DNA molecules. DNA is stretched into air at a liquid-air interface, and can be subsequently ...

    • Shorter Lines Facilitate Reading in Those Who Struggle 

      Schneps, Matthew H.; Thomson, Jenny M.; Sonnert, Gerhard; Pomplun, Marc; Chen, Chen; Heffner-Wong, Amanda (Public Library of Science, 2013)
      People with dyslexia, who ordinarily struggle to read, sometimes remark that reading is easier when e-readers are used. Here, we used eye tracking to observe high school students with dyslexia as they read using these ...

    • Solving the Orientation Specific Constraints in Transcranial Magnetic Stimulation by Rotating Fields 

      Rotem, Assaf; Neef, Andreas; Neef, Nicole E.; Agudelo-Toro, Andres; Rakhmilevitch, David; Paulus, Walter; Moses, Elisha (Public Library of Science, 2014)
      Transcranial Magnetic Stimulation (TMS) is a promising technology for both neurology and psychiatry. Positive treatment outcome has been reported, for instance in double blind, multi-center studies on depression. Nonetheless, ...

    • Sustained drag reduction in a turbulent flow using a low-temperature Leidenfrost surface 

      Saranadhi, Dhananjai; Chen, Dayong; Kleingartner, Justin A.; Srinivasan, Siddarth; Cohen, Robert E.; McKinley, Gareth H. (American Association for the Advancement of Science, 2016)
      Skin friction drag contributes a major portion of the total drag for small and large water vehicles at high Reynolds number (Re). One emerging approach to reducing drag is to use superhydrophobic surfaces to promote slip ...

    • Synchronous Symmetry Breaking in Neurons with Different Neurite Counts 

      Wissner-Gross, Zachary Daniel; Scott, Mark A.; Steinmeyer, Joseph D.; Yanik, Mehmet Fatih (Public Library of Science, 2013)
      As neurons develop, several immature processes (i.e., neurites) grow out of the cell body. Over time, each neuron breaks symmetry when only one of its neurites grows much longer than the rest, becoming an axon. This symmetry ...

    • Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label 

      Carlson, Alicia L.; Fujisaki, Joji; Wu, Juwell; Runnels, Judith M.; Turcotte, Raphaël; Celso, Cristina Lo; Scadden, David T.; Strom, Terry B.; Lin, Charles P. (Public Library of Science, 2013)
      We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after ...