Now showing items 1-3 of 3

    • Dynamics of the Microbiota in Response to Host Infection 

      Belzer, Clara; Gerber, Georg K.; Roeselers, Guus; Delaney, Mary; DuBois, Andrea; Liu, Qing; Belavusava, Vera; Yeliseyev, Vladimir; Houseman, Andres; Onderdonk, Andrew; Cavanaugh, Colleen; Bry, Lynn (Public Library of Science, 2014)
      Longitudinal studies of the microbiota are important for discovering changes in microbial communities that affect the host. The complexity of these ecosystems requires rigorous integrated experimental and computational ...
    • The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification 

      Pukkila-Worley, Read; Feinbaum, Rhonda L.; McEwan, Deborah L.; Conery, Annie L.; Ausubel, Frederick M. (Public Library of Science, 2014)
      Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small molecule xenobiotic toxin that extends survival of Caenorhabditis ...
    • Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection 

      Li, Yuan; Shah-Simpson, Sheena; Okrah, Kwame; Belew, A. Trey; Choi, Jungmin; Caradonna, Kacey L.; Padmanabhan, Prasad; Ndegwa, David M.; Temanni, M. Ramzi; Corrada Bravo, Héctor; El-Sayed, Najib M.; Burleigh, Barbara A. (Public Library of Science, 2016)
      Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T. cruzi infective ...