Browsing FAS Scholarly Articles by Keyword "entropy"
Now showing items 1-7 of 7
-
Characterizing Pseudoentropy and Simplifying Pseudorandom Generator Constructions
(ACM Press, 2012)We provide a characterization of pseudoentropy in terms of hardness of sampling: Let (X,B) be jointly distributed random variables such that B takes values in a polynomial-sized set. We show that B is computationally ... -
Complexes of Native Ubiquitin and Dodecyl Sulfate Illustrate the Nature of Hydrophobic and Electrostatic Interactions in the Binding of Proteins and Surfactants
(American Chemical Society (ACS), 2011)A previous study, using capillary electrophoresis (CE) [J. Am. Chem. Soc.2008, 130, 17384–17393], reported that six discrete complexes of ubiquitin (UBI) and sodium dodecyl sulfate (SDS) form at different concentrations ... -
Mechanism of the Hydrophobic Effect in the Biomolecular Recognition of Arylsulfonamides by Carbonic Anhydrase
(Proceedings of the National Academy of Sciences, 2011)The hydrophobic effect—a rationalization of the insolubility of nonpolar molecules in water—is centrally important to biomolecular recognition. Despite extensive research devoted to the hydrophobic effect, its molecular ... -
Mechanism-Independent Method for Predicting Response to Multidrug Combinations in Bacteria
(Proceedings of the National Academy of Sciences, 2012)Drugs are commonly used in combinations larger than two for treating bacterial infection. However, it is generally impossible to infer directly from the effects of individual drugs the net effect of a multidrug combination. ... -
On Approximating the Entropy of Polynomial Mappings
(2017-09-14)We investigate the complexity of Polynomial Entropy Approximation (PEA): Given a low-degree polynomial mapping p : F^n-> F^m, where F is a finite field, approximate the output entropy H(p(U_n)), where U_n is the uniform ... -
Physical-Organic Chemistry: A Swiss Army Knife
(Wiley-Blackwell, 2015)“Physical-organic chemistry” is the name given to a subfield of chemistry that applies physical-chemical techniques to problems in organic chemistry (especially problems involving reaction mechanisms). “Physical-organic” ... -
Quantifying the Fraction of Missing Information for Hypothesis Testing in Statistical and Genetic Studies
(Institute of Mathematical Statistics, 2008)Many practical studies rely on hypothesis testing procedures applied to data sets with missing information. An important part of the analysis is to determine the impact of the missing data on the performance of the test, ...