Browsing FAS Scholarly Articles by Keyword "genetics of disease"
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Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans
(Public Library of Science, 2012)Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality in the behavior of the nematode C. elegans, which has only eight ... -
A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs
(Public Library of Science, 2011)Hereditary periodic fever syndromes are characterized by recurrent episodes of fever and inflammation with no known pathogenic or autoimmune cause. In humans, several genes have been implicated in this group of diseases, ...