Browsing FAS Scholarly Articles by Keyword "insertional mutagenesis"

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    • Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions 

      Varas, Florencio; de Andres-Aguayo, Luisa; di Tullio, Alessandro; Pantano, Lorena; Notredame, Cedric; Graf, Thomas; Stadtfeld, Matthias; Maherali, Nimet Alia; Hochedlinger, Konrad (Wiley Subscription Services, Inc., A Wiley Company, 2009)
      Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the ...