Browsing FAS Scholarly Articles by Keyword "mutation"
Now showing items 1-3 of 3
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Phenotype Switching and Mutations in Random Environments
(Springer-Verlag, 2012)Cell populations can benefit from changing phenotype when the environment changes. One mechanism for generating these changes is stochastic phenotype switching, whereby cells switch stochastically from one phenotype to ... -
Rapid, Field-Deployable Method for Genotyping and Discovery of Single-Nucleotide Polymorphisms Associated with Drug Resistance in Plasmodium falciparum
(American Society for Microbiology, 2012)Despite efforts to reduce malaria morbidity and mortality, drug-resistant parasites continue to evade control strategies. Recently, emphasis has shifted away from control and toward regional elimination and global eradication ... -
Repeated, Selection-Driven Genome Reduction of Accessory Genes in Experimental Populations
(Public Library of Science, 2012)Genome reduction has been observed in many bacterial lineages that have adapted to specialized environments. The extreme genome degradation seen for obligate pathogens and symbionts appears to be dominated by genetic drift. ...