A Concise Synthesis of the Naphthoic Acid Component of Neocarzinostatin Chromophore Featuring a New Photocyclization Reaction

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Title:	A Concise Synthesis of the Naphthoic Acid Component of Neocarzinostatin Chromophore Featuring a New Photocyclization Reaction
Author:	Hammond, Marlys; Subramanian, Vijaya; Myers, Andrew Note: Order does not necessarily reflect citation order of authors.
Citation:	Myers, Andrew G., Vijaya Subramanian and Marlys Hammond. 1995. A concise synthesis of the naphthoic acid component of neocarzinostatin chromophore featuring a new photocyclization reaction. Tetrahedron Letters 37(5): 587-590.
Access Status:	At the direction of the depositing author this work is not currently accessible through DASH.
Full Text & Related Files:	myers51.pdf (289.0Kb; PDF)
Abstract:	A 6-step synthesis of the naphthoic acid component of the natural antitumor agent neocarzinostatin chromophore is described. The synthetic route employs a 4-bromo-3-methylanisole as the starting material, proceeds in 31-37% yield for the 6 steps, and features as the key step a photocyclization reaction that is an interesting variant of known photocyclization reactions of stilbenes and phenylbutadienes.
Published Version:	http://dx.doi.org/10.1016/0040-4039(95)02268-6
Other Sources:	http://www.chem.harvard.edu/groups/myers/publications.htm
Citable link to this page:	http://nrs.harvard.edu/urn-3:HUL.InstRepos:3119446

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