Synthesis of Highly Enantiomerically Enriched N-Boc-a-amino Ketones from Pseudoephedrine N-Boc-a-amino Acid Amides

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Synthesis of Highly Enantiomerically Enriched N-Boc-a-amino Ketones from Pseudoephedrine N-Boc-a-amino Acid Amides

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Title: Synthesis of Highly Enantiomerically Enriched N-Boc-a-amino Ketones from Pseudoephedrine N-Boc-a-amino Acid Amides
Author: Myers, Andrew; Yoon, Taeyoung

Note: Order does not necessarily reflect citation order of authors.

Citation: Myers, Andrew G. and Taeyoung Yoon. 1995. Synthesis of highly enantiomerically enriched N-Boc-a-amino ketones from pseudoephedrine N-Boc-a-amino acid amides. Tetrahedron Letters 36(52): 9429-9432.
Access Status: At the direction of the depositing author this work is not currently accessible through DASH.
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Abstract: N-Boc-alpha-amino ketones are synthesized efficiently and in high enantiomeric excess by the addition of organolithium and Grignard reagents to pseudoephedrine amides of N-Boc-alpha-amino acids, themselves available by the alkylation of pseudoephedrine glycinamide followed by N-protection.
Published Version: http://dx.doi.org/10.1016/0040-4039(95)02053-5
Other Sources: http://www.chem.harvard.edu/groups/myers/pdf_publications/tetlet_1995_36_9429.pdf
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:3122541

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  • FAS Scholarly Articles [7362]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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