Characterization of Nucleic Acids by Nanopore Analysis

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Characterization of Nucleic Acids by Nanopore Analysis

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Title: Characterization of Nucleic Acids by Nanopore Analysis
Author: Deamer, David W.; Branton, Daniel

Note: Order does not necessarily reflect citation order of authors.

Citation: Deamer, David W. and Daniel Branton. 2002. Characterization of nucleic acids by nanopore analysis. Accounts of Chemical Research 35(10): 817-825.
Access Status: At the direction of the depositing author this work is not currently accessible through DASH.
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Abstract: Single-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade.
Published Version: http://dx.doi.org/10.1021/ar000138m
Other Sources: http://www.mcb.harvard.edu/branton/DeamerBranton2002.pdf
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:3137806

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  • FAS Scholarly Articles [7501]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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