| Title: | Characterization of Nucleic Acids by Nanopore Analysis |
| Author: |
Deamer, David W.; Branton, Daniel
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Deamer, David W. and Daniel Branton. 2002. Characterization of nucleic acids by nanopore analysis. Accounts of Chemical Research 35(10): 817-825. |
| Access Status: | At the direction of the depositing author this work is not currently accessible through DASH. |
| Full Text & Related Files: |
Branton_CharacterizationNucleicAcids.pdf (256.8Kb; PDF)
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| Abstract: | Single-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade. |
| Published Version: | http://dx.doi.org/10.1021/ar000138m |
| Other Sources: | http://www.mcb.harvard.edu/branton/DeamerBranton2002.pdf |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:3137806 |
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