The Gain Paradox
| Title: | The Gain Paradox |
| Author: | Berg, Howard |
| Citation: | Berg, Howard Curtis. 2009. The gain paradox. Progress in Biophysics and Molecular Biology 100(1-3): 2-3. |
| Full Text & Related Files: |
Berg_GainParadox.pdf (105.9Kb; PDF) 
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| Abstract: | Chemoreceptors in Escherichia coli control the activity of a kinase that phosphorylates a response regulator that, in turn, biases the direction of rotation of flagellar motors, affecting the manner in which cells swim. A small change in receptor occupancy induces a large change in kinase activity. This gain is generated by allosteric interactions between receptors, which are arranged in clusters. The idea that such amplification might occur was advanced by [Bray et al., 1998] and [Bray, 2002]. |
| Published Version: | doi:10.1016/j.pbiomolbio.2009.06.001 |
| Terms of Use: | This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4262994 |
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