Fitness Variation Due To Sexual Antagonism and Linkage Disequilibrium

DSpace/Manakin Repository

Fitness Variation Due To Sexual Antagonism and Linkage Disequilibrium

Citable link to this page

. . . . . .

Title: Fitness Variation Due To Sexual Antagonism and Linkage Disequilibrium
Author: Patten, Manus Michael; Haig, David Addison; Ubeda, Francisco

Note: Order does not necessarily reflect citation order of authors.

Citation: Patten, Manus M., David Haig, and Francisco Ubeda. Forthcoming. Fitness variation due to sexual antagonism and linkage disequilibrium. Evolution: International Journal of Organic Evolution 64.
Full Text & Related Files:
Abstract: Extensive fitness variation for sexually antagonistic characters has been detected in nature. However, current population genetic theory suggests that sexual antagonism is unlikely to play a major role in the maintenance of variation. We present a two-locus model of sexual antagonism that is capable of explaining greater fitness variance at equilibrium than previous single-locus models. The second genetic locus provides additional fitness variance in two complementary ways. First, linked loci can maintain gene variants that are lost in single-locus models of evolution, expanding the opportunity for polymorphism. Second, linkage disequilibrium results between any two sexually antagonistic genes, producing an excess of high and low fitness haplotypes. Our results uncover a unique contribution of conflicting selection pressures to the maintenance of variation, which simpler models that neglect genetic architecture overlook.
Published Version: http://www.wiley.com/bw/journal.asp?ref=0014-3820
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4321894

Show full Dublin Core record

This item appears in the following Collection(s)

  • FAS Scholarly Articles [6948]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

Search DASH


Advanced Search
 
 

Submitters