Harvard Medical School
Recent Submissions
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Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
(Springer Science and Business Media LLC, 2023-11-30)The human leukocyte antigen (HLA) locus plays a critical role in complex traits spanning autoimmune and infectious diseases, transplantation, and cancer. While coding variation in HLA genes has been extensively documented, ... -
Dynamic computational phenotyping of human cognition
(Springer Science and Business Media LLC, 2024-02-08)Computational phenotyping has emerged as a powerful tool for characterizing individual variability across a variety of cognitive domains. An individual's computational phenotype is defined as a set of mechanistically ... -
Genomic data in the All of Us Research Program
(Springer Science and Business Media LLC, 2024-02-19)Comprehensively mapping the genetic basis of human disease across diverse individuals is a longstanding goal for the field of human genetics.1-4 The All of Us Research Program is a longitudinal cohort aiming to enroll a ...