Browsing Harvard Medical School by Title
Now showing items 2451-2470 of 18428
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Changes in Screening Colonoscopy Following Medicare Reimbursement and Cost‐sharing Changes
(Wiley, 2019-04-02)Objectives: To compare existing algorithms for classifying screening vs diagnostic colonoscopies and to quantify the increase in screening colonoscopy rates when Medicare began reimbursement in 2001 and when the Affordable ... -
Changes in self-reported HIV testing during South Africa's 2010/2011 national testing campaign: gains and shortfalls
(International AIDS Society, 2016)Objectives: HIV counselling and testing is critical to HIV prevention and treatment efforts. Mass campaigns may be an effective strategy to increase HIV testing in countries with generalized HIV epidemics. We assessed the ... -
Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy
(BioMed Central, 2015)Introduction: The goal was to identify which neurochemicals differ in professional athletes with repetitive brain trauma (RBT) when compared to healthy controls using a relatively new technology, in vivo Localized COrrelated ... -
Changes in the Propofol-Induced Frontal Electroencephalogram in Children With Autism Spectrum Disorder
(2017-05-12)General anesthetic drugs induce characteristic oscillations within brain circuits that can be readily assessed using the electroencephalogram (EEG), allowing a controlled and noninvasive way to study the circuitry of the ... -
Changes in Tobacco Smoke Exposure following the Institution of a Smoke-Free Policy in the Boston Housing Authority
(Public Library of Science, 2015)Introduction: To protect residents from tobacco smoke exposure (TSE), the Boston Housing Authority (BHA) prohibited smoking in BHA-owned apartments beginning in 2012. Our goal was to determine if the smoke-free policy ... -
Changes in water and beverage intake and long-term weight changes: results from three prospective cohort studies
(2013)Objective: To examine the long-term relationship between changes in water and beverage intake and weight change. Subjects Prospective cohort studies of 50 013 women aged 40-64 in the Nurses’ Health Study (NHS, 1986-2006), ... -
CHANGES OF DIASTOLIC FUNCTION IN LATE LIFE AND NON-CARDIAC RISK FACTORS FOR HEART FAILURE IN THE BLACK- PERSPECTIVES ON HEART FAILURE IN HIGH-RISK POPULATIONS
(2021-06-23)Paper 1 Introduction: Diastolic dysfunction is a potent risk factor for heart failure (HF). However, there is limited data regarding longitudinal changes of diastolic function in the very old, who are at the highest risk ... -
Changes of functional connectivity in the left frontoparietal network following aphasic stroke
(Frontiers Media S.A., 2014)Language is an essential higher cognitive function supported by large-scale brain networks. In this study, we investigated functional connectivity changes in the left frontoparietal network (LFPN), a language-cognition ... -
The changing landscape of atherosclerosis
(Springer Science and Business Media LLC, 2021-04-21)Emerging evidence has spurred considerable evolution of concepts of atherosclerosis and called into question many cherished notions. Atherosclerosis risk no longer concentrates in Western countries, but now reaches globally ... -
The Changing Landscape of Molecular Diagnostic Testing: Implications for Academic Medical Centers
(MDPI, 2016)Over the last decade, the field of molecular diagnostics has undergone tremendous transformation, catalyzed by the clinical implementation of next generation sequencing (NGS). As technical capabilities are enhanced and ... -
Changing Mad2 Levels Affects Chromosome Segregation and Spindle Assembly Checkpoint Control in Female Mouse Meiosis I
(Public Library of Science, 2007)The spindle assembly checkpoint (SAC) ensures correct separation of sister chromatids in somatic cells and provokes a cell cycle arrest in metaphase if one chromatid is not correctly attached to the bipolar spindle. Prolonged ... -
Changing Patterns of Spatial Clustering of Schistosomiasis in Southwest China between 1999–2001 and 2007–2008: Assessing Progress toward Eradication after the World Bank Loan Project
(MDPI, 2014)We compared changes in the spatial clustering of schistosomiasis in Southwest China at the conclusion of and six years following the end of the World Bank Loan Project (WBLP), the control strategy of which was focused on ... -
Changing Surgical Antimicrobial Prophylaxis Practices through Education Targeted at Senior Department Leaders
(Cambridge University Press (CUP), 1990)Prescribing antibiotics for perioperative prophylaxis in common surgical procedures presents an ideal target for educational intervention. In this situation, antibiotics are often used inappropriately, with consequent ... -
Changing the Receptor Specificity of Anthrax Toxin
(American Society of Microbiology, 2012)The actions of many bacterial toxins depend on their ability to bind to one or more cell-surface receptors. Anthrax toxin acts by a sequence of events that begins when the protective-antigen (PA) moiety of the toxin binds ... -
Changing the Way We Approach Medically Complex Children: A Screener for Unmet Needs
(2015-06-08)Medically complex children have at least one chronic condition resulting in high service needs, including medication, equipment and multiple subspecialist involvement. Evidence has shown that increased care coordination ... -
Chaotic Signatures of Heart Rate Variability and Its Power Spectrum in Health, Aging and Heart Failure
(Public Library of Science, 2009)A paradox regarding the classic power spectral analysis of heart rate variability (HRV) is whether the characteristic high- (HF) and low-frequency (LF) spectral peaks represent stochastic or chaotic phenomena. Resolution ... -
Chaperone-mediated autophagy degrades mutant p53
(Cold Spring Harbor Laboratory Press, 2013)Missense mutations in the gene TP53, which encodes p53, one of the most important tumor suppressors, are common in human cancers. Accumulated mutant p53 proteins are known to actively contribute to tumor development and ... -
Characterisation of [11C]PR04.MZ in Papio Anubis Baboon: A Selective High-Affinity Radioligand for Quantitative Imaging of the Dopamine Transporter
(Elsevier BV, 2012)N-(4-fluorobut-2-yn-1-yl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (PR04.MZ, 1) is a PET radioligand for the non-invasive exploration of the function of the cerebral dopamine transporter (DAT). A reliable automated process ... -
Characterising Long Non-Coding RNAs (lncRNAs) Associated with a Protective Type 1 Interferon (IFN) Gene Signature in Tumour and Immune cells
(2021-07-19)Type 1 interferons have emerged as critical regulators of cancer immunity. By inducing the transcription of interferon-stimulated genes (ISGs), these cytokines can directly inhibit tumour proliferation and mediate apoptosis, ... -
Characteristics and Impact of Drug Detailing for Gabapentin
(Public Library of Science, 2007)Background: Sales visits by pharmaceutical representatives (“drug detailing”) are common, but little is known about the content of these visits or about the impact of visit characteristics on prescribing behavior. In this ...