Browsing Harvard Medical School by Title
Now showing items 2926-2945 of 18428
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Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance.
(American Society for Clinical Investigation, 1990)The present studies investigated the expression of the two PDGF genes (c-sis/PDGF-2 and PDGF-1) and the PDGF-receptor b gene (PDGF-R) in 34 primary human astrocytomas. Northern blot analysis demonstrated the coexpression ... -
Coffee and Caffeine Consumption in Relation to Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Postmenopausal Women
(American Diabetes Association, 2011)OBJECTIVE: Coffee consumption has been inversely associated with type 2 diabetes risk, but its mechanisms are largely unknown. We aimed to examine whether plasma levels of sex hormones and sex hormone–binding globulin ... -
Coffee and cancer risk: A meta-analysis of prospective observational studies
(Nature Publishing Group, 2016)Meta-analyses on coffee and cancer incidence mainly restricted to limited cancers. We carried out a more comprehensive meta-analysis of cohort studies to explore association between coffee and most cancer types. We conducted ... -
Coffee Consumption and Risk of Cardiovascular Diseases and All-Cause Mortality Among Men With Type 2 Diabetes
(American Diabetes Association, 2009)OBJECTIVE: Coffee consumption has been linked to detrimental acute metabolic and hemodynamic effects. We investigated coffee consumption in relation to risk of CVDs and mortality in diabetic men. RESEARCH DESIGN AND METHODS: ... -
Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer
(Springer Science + Business Media, 2008)We evaluated whether genetic variability, as well as menopausal status, modify the association between coffee intake and risk of ovarian cancer. Risk factor information and biologic specimens from three large epidemiological ... -
Cognition and the Take-Up of Subsidized Drug Benefits by Medicare Beneficiaries
(2016-05-17)Importance: Take-up of the Medicare Part D low-income subsidy (LIS) by eligible beneficiaries has been low despite the attractive drug coverage it offers at no cost to beneficiaries and outreach efforts by the Social ... -
Cognitive and Brain Reserve and the Risk of Postoperative Delirium in Older Patients: Analysis of Data From a Prospective Observational Study
(Elsevier BV, 2014-11-01)Background Cognitive and brain reserve theories suggest that aspects of neural architecture or cognitive processes modify the impact of neuropathological processes on cognitive outcomes. While frequently studied in the ... -
Cognitive and Other Adverse Effects of Diphenhydramine Use in Hospitalized Older Patients
(American Medical Association (AMA), 2001) -
Cognitive and Physical Demands of Activities of Daily Living In Older Adults: Validation of Expert Panel Ratings: The SAGES Functional Measures Working Group
(2015)Background: Difficulties with performance of functional activities may result from cognitive and/or physical impairments. To date, there has not been a clear delineation of the physical and cognitive demands of activities ... -
Cognitive changes associated with switching to frequent nocturnal hemodialysis or renal transplantation
(BioMed Central, 2016)Background: It is uncertain whether switching to frequent nocturnal hemodialysis improves cognitive function in well-dialyzed patients and how this compares to patients who receive a kidney transplant. Methods: We conducted ... -
Cognitive deficits and magnetic resonance spectroscopy in adult monozygotic twins with lead poisoning.
(2004)Seventy-one-year-old identical twin brothers with chronic lead poisoning were identified from an occupational medicine clinic roster. Both were retired painters, but one brother (J.G.) primarily removed paint and had a ... -
Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspects
(Springer Science + Business Media, 1999)Seeking to unite psychological and biological approaches, this paper links cognitive and cellular hypotheses and data about thought and language abnormalities in schizophrenia. The common thread, it is proposed, is a ... -
Cognitive Enhancement Therapy Improves Frontolimbic Regulation of Emotion in Alcohol and/or Cannabis Misusing Schizophrenia: A Preliminary Study
(Frontiers Media S.A., 2016)Individuals with schizophrenia who misuse substances are burdened with impairments in emotion regulation. Cognitive enhancement therapy (CET) may address these problems by enhancing prefrontal brain function. A small sample ... -
COGNITIVE FUNCTION IN ELDERLY PATIENTS AFTER CARDIAC SURGERY: A SECONDARY ANALYSIS OF THE MINDDS TRIAL
(2023-05-03)Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients characterized by attention deficit, impaired memory and concentration that can last several months. POCD has been formally recognized ... -
Cognitive Function Is Disrupted by Both Hypo- and Hyperglycemia in School-Aged Children With Type 1 Diabetes: A Field Study
(American Diabetes Association, 2009)Objective: We developed a field procedure using personal digital assistant (PDA) technology to test the hypothesis that naturally occurring episodes of hypo- and hyperglycemia are associated with deterioration in cognitive ... -
Cognitive Functioning and Academic Performance in Elementary School Children with Anxious/Depressed and Withdrawn Symptoms
(Bentham Science Publishers Ltd., 2010)Rationale: Few studies have evaluated the relationship between depressive symptomatology and neuropsychological performance in children without symptomatic depression.Objectives: This study determined the relationship ... -
Cognitive Performance in a High-Functioning Community-Dwelling Elderly Population
(Oxford University Press (OUP), 1993-07-01)Background: The purpose of this study was to examine the role of demographic factors as predictors of cognitive performance in a high-functioning, community-dwelling elderly population. Methods: The study cohort consisted ... -
Cognitive profile and brain morphological changes in obstructive sleep apnea
(Elsevier BV, 2011-01) -
Cognitive Rehabilitation Interventions for Neglect and Related Disorders: Moving from Bench to Bedside in Stroke Patients
(Massachusetts Institute of Technology Press (MIT Press), 2006) -
Cognitive Remediation in Schizophrenia
(Korean College of Neuropsychopharmacology, 2012)Cognitive deficits in schizophrenia are pervasive, severe, and largely independent of the positive and negative symptoms of the illness. These deficits are increasingly considered to be core features of schizophrenia with ...