Browsing Harvard Medical School by Title
Now showing items 4785-4804 of 18428
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Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis
(BioMed Central, 2014)Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective medical therapies. Recent research has focused on identifying the biological processes essential to the development and ... -
The Doctor’s New Black Bag: Instructional Technology and the Tools of the 21st Century Physician
(Co-Action Publishing, 2006) -
Documentation and Localization of Force-mediated Filamin A Domain Perturbations in Moving Cells
(2014)Endogenously and externally generated mechanical forces influence diverse cellular activities, a phenomenon defined as mechanotransduction. Deformation of protein domains by application of stress, previously documented to ... -
Documentation of Body Mass Index and Control of Associated Risk Factors in a Large Primary Care Network
(BioMed Central, 2009)Background: Body mass index (BMI) will be a reportable health measure in the United States (US) through implementation of Healthcare Effectiveness Data and Information Set (HEDIS) guidelines. We evaluated current documentation ... -
Does a New Polyomavirus Contribute to Merkel Cell Carcinoma?
(BioMed Central, 2008)A new technique designed to hunt for non-human transcripts has identified a novel SV40-like virus present in the majority of Merkel cell carcinomas. Here we examine what it will take to determine whether or not this virus ... -
Does a woman’s educational attainment influence in vitro fertilization outcomes?
(Elsevier BV, 2011)The association between educational level and cycle outcomes was quantified by applying multivariable logistic and linear regression within a prospective cohort of 2,569 women commencing their first in vitro fertilization ... -
Does Abnormal Sleep Impair Memory Consolidation in Schizophrenia?
(Frontiers Media, 2009)Although disturbed sleep is a prominent feature of schizophrenia, its relation to the pathophysiology, signs, and symptoms of schizophrenia remains poorly understood. Sleep disturbances are well known to impair cognition ... -
Does Adjunctive Tigecycline Improve Outcomes in Severe-Complicated, Nonoperative Clostridium difficile Infection?
(Oxford University Press (OUP), 2017)Severe Clostridium difficile infection is associated with a high rate of mortality; however, the optimal treatment for severe- complicated infection remains uncertain for patients who are not candidates for surgical ... -
Does amyloid deposition produce a specific atrophic signature in cognitively normal subjects?☆
(Elsevier, 2013)The objective of our study was to evaluate whether cognitively normal (CN) elderly participants showing elevated cortical beta-amyloid (Aβ) deposition have a consistent neuroanatomical signature of brain atrophy that may ... -
Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency?
(Association for Research in Vision and Ophthalmology, 1999)PURPOSE: The current investigators have shown that androgen treatment suppresses inflammation and stimulates the function of lacrimal glands in mouse models of Sjögren's syndrome. Recently, others have hypothesized that ... -
Does Arterial Spin-Labeling MR Imaging–measured Tumor Perfusion Correlate With Renal Cell Cancer Response to Antiangiogenic Therapy in a Mouse Model?
(Radiological Society of North America (RSNA), 2009-06)Purpose: To determine whether arterial spin-labeling (ASL) magnetic resonance (MR) imaging findings at baseline and early during antiangiogenic therapy can predict later resistance to therapy. Materials and Methods: ... -
Does Autoimmune Pancreatitis Increase the Risk of Pancreatic Carcinoma?
(Ovid Technologies (Wolters Kluwer Health), 2013)OBJECTIVES: To estimate the risk of malignancy in autoimmune pancreatitis (AIP). METHODS: We examined resected pancreata to compare the prevalence of pancreatic intraepithelial neoplasia (PanIN) in 28 cases of AIP and ... -
Does Being Overweight Really Reduce Mortality?
(2013)There is indisputable evidence from epidemiologic and clinical studies that being overweight and obese elevates the risk of developing debilitating and costly chronic diseases, including hypertension, hypercholesterolemia, ... -
Does calcium channel blockade have a role in prevention of expression of sepsis in renal transplant recipients?
(Dove Medical Press, 2016)Many antihypertensive agents have been demonstrated to assist in preservation of kidney function, among them those that modulate calcium channels. Calcium channel blockers may also be of value in protecting hemodialysis ... -
Does compensatory neural activity survive old-old age?
(Elsevier BV, 2011)One mechanism that may allow older adults to continue to successfully perform certain cognitive tasks is to allocate more resources than their younger counterparts. Most prior studies have not included individuals beyond ... -
Does Diabetes Always Confer Coronary Heart Disease Risk Equivalent to a Prior Myocardial Infarction?
(American Diabetes Association, 2011) -
Does Diet Affect Breast Cancer Risk?
(BioMed Central, 2004)The role of specific dietary factors in breast cancer causation is not completely resolved. Results from prospective studies do not support the concept that fat intake in middle life has a major relation to breast cancer ... -
Does duration of physical activity bouts matter for adiposity and metabolic syndrome? A cross-sectional study of older British men
(BioMed Central, 2016)Background: Older adults have low physical activity(PA) and high sedentary behaviour(SB) levels. We investigate how total volume and specific patterns of moderate to vigorous PA(MVPA), light PA(LPA) and SB are related to ... -
Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?
(Public Library of Science, 2006)Inadequate healing of myocardial infarction may contribute to local expansion of the infarct, frequently leading to chamber dilation, heart failure, or myocardial rupture. Experimental evidence in mouse models suggests ... -
Does Glucose Variability Influence the Relationship Between Mean Plasma Glucose and \(HbA_{1c}\) Levels in Type 1 and Type 2 Diabetic Patients?
(American Diabetes Association, 2011)Objective: The A1C-Derived Average Glucose (ADAG) study demonstrated a linear relationship between \(HbA_{1c}\) and mean plasma glucose (MPG). As glucose variability (GV) may contribute to glycation, we examined the ...