Browsing Harvard Medical School by Title
Now showing items 5062-5081 of 18424
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Early Results of the Meaningful Use Program for Electronic Health Records
(Massachusetts Medical Society, 2013-02-21) -
Early Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock
(New England Journal of Medicine (NEJM/MMS), 1999)Background The leading cause of death in patients hospitalized for acute myocardial infarction is cardiogenic shock. We conducted a randomized trial to evaluate early revascularization in patients with cardiogenic shock. ... -
Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis
(Nature Publishing Group, 2016)Multifactorial mechanisms underlying late-onset Alzheimer's disease (LOAD) are poorly characterized from an integrative perspective. Here spatiotemporal alterations in brain amyloid-β deposition, metabolism, vascular, ... -
Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study
(BioMed Central, 2015)Background: The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posits ... -
Early vs. Late Chemoradiation Therapy and the Postoperative Interval to Adjuvant Therapy Do Not Correspond to Local Recurrence in Resected Pancreatic Cancer
(2015)Objective: Standard postoperative therapy for pancreatic cancer consists of both chemotherapy alone and chemoradiation. We sought to investigate whether the sequence of chemotherapy and chemoradiation and overall time to ... -
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging
(2012)All juvenile NOD mice exhibit insulitis, but there is substantial variation in their progression to diabetes. We demonstrate that a patient-validated magnetic-resonance-imaging (MRI) strategy to non-invasively visualize ... -
Early-Adulthood Cardiovascular Disease Risk Factor Profiles Among Individuals With and Without Diabetes in the Framingham Heart Study
(American Diabetes Association, 2013)OBJECTIVE Many studies of diabetes have examined risk factors at the time of diabetes diagnosis instead of considering the lifetime burden of adverse risk factor levels. We examined the 30-year cardiovascular disease (CVD) ... -
Early-stage clear cell tubulopapillary renal cell carcinoma: imaging features and distinction from clear cell and papillary subtypes
(Springer Nature, 2016)Purpose: Clear cell tubulopapillary renal cell carcinoma (CCTPRCC) is a recently described, low grade subtype of renal cancer. We determined if imaging features could be used to distinguish early-stage CCTPRCC from ... -
East meets West: ethnic differences in epidemiology and clinical behaviors of lung cancer between East Asians and Caucasians
(Sun Yat-sen University Cancer Center, 2011)Lung cancer is the leading cause of cancer death worldwide, with large variation of the incidence and mortality across regions. Although the mortality of lung cancer has been decreasing, or steady in the US, it has been ... -
Eating Attitudes and Food Intakes of Elite Adolescent Female Figure Skaters: a Cross Sectional Study
(BioMed Central, 2012)Background: Elite adolescent female figure skaters compete in an aesthetic-based sport that values thin builds and lithe figures. To conform to the sport’s physical requirements, skaters may alter their eating patterns in ... -
Eating Disorders and Disordered Eating in Different Cultures
(1995)Clinical experience and research have moved the field toward greater recognition and differentiation of eating disorders as independent categories of mental disorder. Shorter's historical analysis, however, suggests that ... -
The EBNA3 Family of Epstein-Barr Virus Nuclear Proteins Associates with the USP46/USP12 Deubiquitination Complexes to Regulate Lymphoblastoid Cell Line Growth
(Public Library of Science, 2015)The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the CDKN2A tumor suppressor gene products p16INK4A ... -
Ebola Virus Epidemiology and Evolution in Nigeria
(Oxford University Press, 2016)Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV ... -
Ebp1 Sumoylation, Regulated by TLS/FUS E3 Ligase, Is Required for Its Anti-Proliferative Activity
(Nature Publishing Group, 2010)Ebp1, an ErbB3 receptor-binding protein, inhibits cell proliferation and acts as a putative tumor suppressor. Ebp1 translocates into the nucleus and functions as a transcription co-repressor for E2F-1. Here, we show that ... -
EBV-Positive Diffuse Large B-Cell Lymphoma in a Human T-Lymphotropic Virus Type 1 Carrier
(Springer Science and Business Media LLC, 2009-07-06)The development of B-cell lymphomas has been seldom described in HTLV-1 carriers. We present the case of an elderly Peruvian HTLV-1 carrier who was diagnosed with EBV-positive diffuse large B-cell lymphoma. Despite an ... -
eccDNAs are apoptotic products with high innate immunostimulatory activity
(Springer Science and Business Media LLC, 2021-10-20) -
Ecdysone Signaling at Metamorphosis Triggers Apoptosis of Drosophila Abdominal Muscles
(Elsevier BV, 2013-11-15)One of the most dramatic examples of programmed cell death occurs during Drosophila metamorphosis, when most of the larval tissues are destroyed in a process termed histolysis. Much of our understanding of this process ... -
ECG Morphological Variability in Beat Space for Risk Stratification After Acute Coronary Syndrome
(Blackwell Publishing Ltd, 2014)Background: Identification of patients who are at high risk of adverse cardiovascular events after an acute coronary syndrome (ACS) remains a major challenge in clinical cardiology. We hypothesized that quantifying variability ... -
Echocardiographic Predictors of Mortality in Patients with Pulmonary Hypertension and Cardiopulmonary Comorbidities
(Public Library of Science, 2015)Objective: We aimed to identify the echocardiographic measures associated with survival in a patient population with a high prevalence of co-morbid cardiovascular and pulmonary disease that have significantly elevated ... -
Echocardiography Practice, Training and Accreditation in the Intensive Care: Document for the World Interactive Network Focused on Critical Ultrasound (WINFOCUS)
(BioMed Central, 2008)Echocardiography is increasingly used in the management of the critically ill patient as a non-invasive diagnostic and monitoring tool. Whilst in few countries specialized national training schemes for intensive care unit ...