Browsing Harvard Medical School by Title

Now showing items 5190-5209 of 18428

    • The effect of musical expertise on the representation of space 

      Lega, Carlotta; Cattaneo, Zaira; Merabet, Lotfi B.; Vecchi, Tomaso; Cucchi, Silvia (Frontiers Media S.A., 2014)
      Consistent evidence suggests that pitch height may be represented in a spatial format, having both a vertical and a horizontal representation. The spatial representation of pitch height results into response compatibility ...

    • Effect of Natalizumab Treatment on Circulating Plasmacytoid Dendritic Cells: A Cross-Sectional Observational Study in Patients with Multiple Sclerosis 

      Kivisäkk, Pia; Francois, Katiana; Mbianda, Julvet; Gandhi, Roopali; Weiner, Howard L.; Khoury, Samia J. (Public Library of Science, 2014)
      Objectives: Dendritic cells (DCs) serve a critical role both in promoting and inhibiting adaptive immunity. The goal of this study was to investigate the effect of natalizumab (NTZ) treatment on DC numbers, phenotype, and ...

    • Effect of negative pressure wound therapy on wound healing 

      Huang, Chenyu; Leavitt, Tripp; Bayer, Lauren; Orgill, Dennis Paul (Elsevier BV, 2014)

    • The effect of neoadjuvant chemoradiation therapy on the prognostic value of lymph nodes after rectal cancer surgery 

      Klos, Coen L.; Shellito, Paul Clarke; Rattner, David William; Hodin, Richard; Cusack, James C.; Bordeianou, Liliana Grigorievna; Sylla, Patricia; Hong, Theodore Sunki; Blaszkowsky, Lawrence Scott; Ryan, Davis P.; Lauwers, Gregory Y.; Chang, Yu Chiao; Berger, David Lawrence (Elsevier BV, 2010)
      Background: Neoadjuvant therapy may affect the prognostic impact of total lymph node harvests and lymph node positivity after surgery for rectal cancer. Methods: We performed a retrospective review of 390 consecutive ...

    • Effect of non-pharmaceutical interventions to contain COVID-19 in China 

      Lai, Shengjie; Ruktanonchai, Nick W; Zhou, Liangcai; Prosper, Olivia; Luo, Wei; Floyd, Jessica R; Wesolowski, Amy; Santillana, Mauricio; Zhang, Chi; Du, Xiangjun; Yu, Hongjie; Tatem, Andrew J
      On March 11, 2020, the World Health Organization declared COVID-19 a pandemic1. The outbreak containment strategies in China based on non-pharmaceutical interventions (NPIs) appear to be effective2, but quantitative research ...

    • Effect of Nonpayment for Preventable Infections in U.S. Hospitals 

      Lee, Grace M.; Kleinman, Kenneth Paul; Soumerai, Stephen Bertram; Tse, Alison; Cole, David; Fridkin, Scott K.; Horan, Teresa; Platt, Richard; Gay, Charlene; Kassler, William; Goldmann, Donald Alan; Jernigan, John; Jha, Ashish Kumar (New England Journal of Medicine (NEJM/MMS), 2012)
      Background In October 2008, the Centers for Medicare and Medicaid Services (CMS) discontinued additional payments for certain hospital-acquired conditions that were deemed preventable. The effect of this policy on rates ...

    • The effect of osteopontin and osteopontin-derived peptides on preterm brain injury 

      Albertsson, Anna-Maj; Zhang, Xiaoli; Leavenworth, Jianmei; Bi, Dan; Nair, Syam; Qiao, Lili; Hagberg, Henrik; Mallard, Carina; Cantor, Harvey; Wang, Xiaoyang (BioMed Central, 2014)
      Background: Osteopontin (OPN) is a highly phosphorylated sialoprotein and a soluble cytokine that is widely expressed in a variety of tissues, including the brain. OPN and OPN-derived peptides have been suggested to have ...

    • The Effect of Particulate Air Pollution on Emergency Admissions for Myocardial Infarction: A Multicity Case-Crossover Analysis 

      Zanobetti, Antonella; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2005)
      Recently, attention has focused on whether particulate air pollution is a specific trigger of myocardial infarction (MI). The results of several studies of single locations assessing the effects of ambient particular matter ...

    • Effect of pay for performance on the management and outcomes of hypertension in the United Kingdom: interrupted time series study 

      Serumaga, B.; Ross-Degnan, Dennis; Avery, A. J.; Elliott, R. A.; Majumdar, S. R.; Zhang, Fang; Soumerai, Stephen Bertram (BMJ, 2011)
      Objective To assess the impact of a pay for performance incentive on quality of care and outcomes among UK patients with hypertension in primary care. Design Interrupted time series. Setting The Health Improvement ...

    • Effect of Pediatric Behavioral Health Screening and Colocated Services on Ambulatory and Inpatient Utilization 

      Hacker, Karen; Penfold, Robert B.; Arsenault, Lisa Nicole; Zhang, Fang; Soumerai, Stephen Bertram; Wissow, Lawrence S. (American Psychiatric Publishing, 2015)
      Objective The study sought to determine the impact of a pediatric behavioral health (BH) screening and co-location model on BH care utilization Methods In 2003, Cambridge Health Alliance, a Massachusetts public ...

    • Effect of PEG Pairing on the Efficiency of Cancer-Targeting Liposomes 

      Saw, Phei Er; Park, Jinho; Lee, Eunbeol; Ahn, Sukyung; Lee, Jinju; Kim, Hyungjun; Kim, Jinjoo; Choi, Minsuk; Farokhzad, Omid C.; Jon, Sangyong (Ivyspring International Publisher, 2015)
      Standardized poly(ethylene glycol)-modified (PEGylated) liposomes, which have been widely used in research as well as in pre-clinical and clinical studies, are typically constructed using PEG with a molecular weight of ...

    • Effect of Penetrating Keratoplasty and Keratoprosthesis Implantation on the Posterior Segment of the Eye 

      Črnej, Alja; Omoto, Masahiro; Dohlman, Thomas H.; Gonzalez-Andrades, Miguel; Paschalis, Eleftherios I.; Cruzat, Andrea; Vu, T. H. Khanh; Doorenbos, Marianne; Chen, Dong Feng; Dohlman, Claes H.; Dana, Reza (The Association for Research in Vision and Ophthalmology, 2016)
      Purpose To compare the effects of post-penetrating keratoplasty (PK) and post-keratoprosthesis (KPro) surgery-related inflammation on the posterior segment of the eye and to assess inhibition of tumor necrosis factor alpha ...

    • The Effect of Perioperative Ketorolac on the Clinical Failure Rate of Meniscal Repair 

      Proffen, Benedikt L.; Nielson, Jason H.; Zurakowski, David; Micheli, Lyle J.; Curtis, Christine; Murray, Martha M. (2014)
      Background: There has been recent interest in the effect of nonsteroidal anti-inflammatory medications on musculoskeletal healing. No studies have yet addressed the effect of these medications on meniscal healing. Hypothesis ...

    • Effect of Phage on the Infectivity of Vibrio cholerae and Emergence of Genetic Variants 

      Zahid, M. Hasan; Udden, S. Nashir; Faruque, A. G.; Calderwood, Stephen B.; Mekalanos, John J.; Faruque, Shah M. (American Society for Microbiology, 2008)
      Seasonal epidemics of cholera in Bangladesh are self-limited in nature, presumably due to phage predation of the causative Vibrio cholerae during the late stage of an epidemic, when cholera patients excrete large quantities ...

    • Effect of pharmacologic agents on the function of the ischemic heart 

      Maroko, Peter R.; Libby, Peter; Braunwald, Eugene (Elsevier BV, 1973)
      Since isoproterenol, tachycardia induced by atrial pacing, propranolol and Hyaluronidase alter the extent and severity of cardiac damage after coronary occlusion, their effects on the function of the severely ischemic heart ...

    • Effect of Phosphodiesterase Inhibition on Insulin Resistance in Obese Individuals 

      Ho, Jennifer E.; Arora, Pankaj; Walford, Geoffrey A.; Ghorbani, Anahita; Guanaga, Derek P.; Dhakal, Bishnu P.; Nathan, Daniel I.; Buys, Emmanuel S.; Florez, Jose C.; Newton‐Cheh, Christopher; Lewis, Gregory D.; Wang, Thomas J. (Blackwell Publishing Ltd, 2014)
      Background: Obesity is associated with cardiometabolic disease, including insulin resistance (IR) and diabetes. Cyclic guanosine monophosphate (cGMP) signaling affects energy balance, IR, and glucose metabolism in experimental ...

    • Effect of Portal Glucose Sensing on Systemic Glucose Levels in SD and ZDF Rats 

      Pal, Atanu; Rhoads, David B.; Tavakkoli, Ali (Public Library of Science, 2016)
      Background: The global epidemic of Type-2-Diabetes (T2D) highlights the need for novel therapeutic targets and agents. Roux-en-Y-Gastric-Bypass (RYGB) is the most effective treatment. Studies investigating the mechanisms ...

    • Effect of Preterm Birth on Postnatal Apolipoprotein and Adipocytokine Profiles 

      Hellgren, Gunnel; Engstrom, Eva; Smith, Lois Elaine Hodgson; Löfqvist, Chatarina; Hellström, Ann (S. Karger AG, 2015)
      BACKGROUND: Critical metabolic changes preparing for ex utero life may occur at the fetal age of approximately 28-32 weeks, and preterm birth <28 weeks postmenstrual age (PMA) may affect these pathways. Children born <28 ...

    • The effect of primary organic particles on emergency hospital admissions among the elderly in 3 US cities 

      Kioumourtzoglou, Marianthi-Anna; Zanobetti, Antonella; Schwartz, Joel D; Coull, Brent A; Dominici, Francesca; Suh, Helen H (BioMed Central, 2013)
      Background: Fine particle (PM2.5) pollution related to combustion sources has been linked to a variety of adverse health outcomes. Although poorly understood, it is possible that organic carbon (OC) species, particularly ...

    • Effect of processing time and storage on fibrinogen content of EDTA plasma assayed by radial immunodiffusion. 

      Kinlay, Scott; Gleeson, M; Dobson, A; Heller, R (American Association for Clinical Chemistry, 1992)