Browsing Harvard Medical School by Title
Now showing items 5198-5217 of 18424
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Effect of pay for performance on the management and outcomes of hypertension in the United Kingdom: interrupted time series study
(BMJ, 2011)Objective To assess the impact of a pay for performance incentive on quality of care and outcomes among UK patients with hypertension in primary care. Design Interrupted time series. Setting The Health Improvement ... -
Effect of Pediatric Behavioral Health Screening and Colocated Services on Ambulatory and Inpatient Utilization
(American Psychiatric Publishing, 2015)Objective The study sought to determine the impact of a pediatric behavioral health (BH) screening and co-location model on BH care utilization Methods In 2003, Cambridge Health Alliance, a Massachusetts public ... -
Effect of PEG Pairing on the Efficiency of Cancer-Targeting Liposomes
(Ivyspring International Publisher, 2015)Standardized poly(ethylene glycol)-modified (PEGylated) liposomes, which have been widely used in research as well as in pre-clinical and clinical studies, are typically constructed using PEG with a molecular weight of ... -
Effect of Penetrating Keratoplasty and Keratoprosthesis Implantation on the Posterior Segment of the Eye
(The Association for Research in Vision and Ophthalmology, 2016)Purpose To compare the effects of post-penetrating keratoplasty (PK) and post-keratoprosthesis (KPro) surgery-related inflammation on the posterior segment of the eye and to assess inhibition of tumor necrosis factor alpha ... -
The Effect of Perioperative Ketorolac on the Clinical Failure Rate of Meniscal Repair
(2014)Background: There has been recent interest in the effect of nonsteroidal anti-inflammatory medications on musculoskeletal healing. No studies have yet addressed the effect of these medications on meniscal healing. Hypothesis ... -
Effect of Phage on the Infectivity of Vibrio cholerae and Emergence of Genetic Variants
(American Society for Microbiology, 2008)Seasonal epidemics of cholera in Bangladesh are self-limited in nature, presumably due to phage predation of the causative Vibrio cholerae during the late stage of an epidemic, when cholera patients excrete large quantities ... -
Effect of pharmacologic agents on the function of the ischemic heart
(Elsevier BV, 1973)Since isoproterenol, tachycardia induced by atrial pacing, propranolol and Hyaluronidase alter the extent and severity of cardiac damage after coronary occlusion, their effects on the function of the severely ischemic heart ... -
Effect of Phosphodiesterase Inhibition on Insulin Resistance in Obese Individuals
(Blackwell Publishing Ltd, 2014)Background: Obesity is associated with cardiometabolic disease, including insulin resistance (IR) and diabetes. Cyclic guanosine monophosphate (cGMP) signaling affects energy balance, IR, and glucose metabolism in experimental ... -
Effect of Portal Glucose Sensing on Systemic Glucose Levels in SD and ZDF Rats
(Public Library of Science, 2016)Background: The global epidemic of Type-2-Diabetes (T2D) highlights the need for novel therapeutic targets and agents. Roux-en-Y-Gastric-Bypass (RYGB) is the most effective treatment. Studies investigating the mechanisms ... -
Effect of Preterm Birth on Postnatal Apolipoprotein and Adipocytokine Profiles
(S. Karger AG, 2015)BACKGROUND: Critical metabolic changes preparing for ex utero life may occur at the fetal age of approximately 28-32 weeks, and preterm birth <28 weeks postmenstrual age (PMA) may affect these pathways. Children born <28 ... -
The effect of primary organic particles on emergency hospital admissions among the elderly in 3 US cities
(BioMed Central, 2013)Background: Fine particle (PM2.5) pollution related to combustion sources has been linked to a variety of adverse health outcomes. Although poorly understood, it is possible that organic carbon (OC) species, particularly ... -
Effect of processing time and storage on fibrinogen content of EDTA plasma assayed by radial immunodiffusion.
(American Association for Clinical Chemistry, 1992) -
Effect of Progestin-Dominant Combined Oral Contraception on Uterine Fibroid Development
(Austin Publishing Group, 2017-11-29)Background: Combined oral contraception blocks the endogenous ovarian steroid secretion that stabilizes the hormonal environment. Monophasic, progestin-dominant, contraceptives may lead to regression of estrogendependent ... -
The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting
(Frontiers Media S.A., 2013)Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: ... -
Effect of Rare Variants in ADRB2 on Risk of Severe Exacerbations and Symptom Control During Longacting β Agonist Treatment in a Multiethnic Asthma Population: A Genetic Study
(Elsevier BV, 2014-03)Background Severe adverse life-threatening events associated with long-acting beta agonists (LABA) use have caused the FDA to review LABA safety which has resulted in a boxed warning and a mandatory LABA safety study in ... -
Effect of Reducing Interns' Work Hours on Serious Medical Errors in Intensive Care Units
(Massachusetts Medical Society, 2004-10-28)BACKGROUND Although sleep deprivation has been shown to impair neurobehavioral performance, few studies have measured its effects on medical errors. METHODS We conducted a prospective, randomized study comparing the ... -
EFFECT OF ROD DIAMETER ON BIOMECHANICS OF POSTERIOR LATERAL MASS FIXATION IN CERVICAL SPINE: AN IN VITRO AND IN SILICO STUDY
(2021-06-23)Spinal fusion is a common surgical method often performed for the treatment of various disorders associated with the spine, including degenerative spondylosis, spondylolisthesis, secondary to trauma, or other clinical ... -
Effect of Roux-en-Y Gastric Bypass Surgery on Bile Acid Metabolism in Normal and Obese Diabetic Rats
(Public Library of Science, 2015)In addition to classic functions of facilitating hepatobiliary secretion and intestinal absorption of lipophilic nutrients, bile acids (BA) are also endocrine factors and regulate glucose and lipid metabolism. Recent data ... -
Effect of Ruboxistaurin on Blood–Retinal Barrier Permeability in Relation to Severity of Leakage in Diabetic Macular Edema
(Association for Research in Vision and Ophthalmology (ARVO), 2005)Purpose. The purpose of the study was to investigate the effect of orally administered ruboxistaurin (RBX, LY333531), a selective protein kinase C β inhibitor, on the permeability of the blood–retinal barrier in patients ...