Browsing Harvard Medical School by Title
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Exposure measurement error in PM2.5 health effects studies: A pooled analysis of eight personal exposure validation studies
(BioMed Central, 2014)Background: Exposure measurement error is a concern in long-term PM2.5 health studies using ambient concentrations as exposures. We assessed error magnitude by estimating calibration coefficients as the association between ... -
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes
(WILEY-VCH Verlag, 2013)Immunoglobulins, antigens and complement can assemble to form immune complexes (IC). ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs, submicron extracellular vesicles termed microparticles ... -
Exposure of Engineered Nanomaterials and Its Potential Contribution to Alzheimer\'s Pathophysiology
(OMICS Publishing Group, 2013) -
Exposure sources, amounts and time course of gluten ingestion and excretion in patients with coeliac disease on a gluten‐free diet
(Wiley, 2020-11)Background A major deficit in understanding and improving treatment in coeliac disease (CD) is the lack of empiric data on real world gluten exposure. Aims To estimate gluten exposure on a gluten‐free diet (GFD) using ... -
Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants
(National Institute of Environmental Health Sciences, 2008)Objective: We previously demonstrated that exposure to polyvinyl chloride plastic medical devices containing di(2-ethylhexyl) phthalate (DEHP) was associated with higher urinary concentrations of several DEHP metabolites ... -
Exposure to Childhood Abuse and Later Substance Use: Indirect Effects of Emotion Dysregulation and Exposure to Trauma
(John Wiley and Sons Inc., 2016)Little is known about how emotion dysregulation (ED) and trauma exposure differentially affect the relationship between abuse in childhood and adult substance use. We examined associations between child abuse, trauma ... -
Exposure to Fumonisins and the Occurrence of Neural Tube Defects Along the Texas–Mexico Border
(National Institute of Environmental Health Sciences, 2005)Along the Texas–Mexico border, the prevalence of neural tube defects (NTDs) among Mexican-American women doubled during 1990–1991. The human outbreak began during the same crop year as epizootics attributed to exposure to ... -
Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women
(National Institute of Environmental Health Sciences, 2016)Background: Green, natural environments may ameliorate adverse environmental exposures (e.g., air pollution, noise, and extreme heat), increase physical activity and social engagement, and lower stress. Objectives: We aimed ... -
Exposure to Metal-rich Particulate Matter Modifies the Expression of Candidate Micrornas in Peripheral Blood Leukocytes
(National Institute of Environmental Health Sciences, 2010)Background: Altered patterns of gene expression mediate the effects of particulate matter (PM) on human health, but mechanisms through which PM modifies gene expression are largely undetermined. MicroRNAs (miRNAs) are ... -
Exposure to Polycyclic Aromatic Hydrocarbons, Plasma Cytokines, and Heart Rate Variability
(Nature Publishing Group, 2016)Epidemiological studies have suggested associations between polycyclic aromatic hydrocarbons (PAHs) and heart rate variability (HRV). However, the roles of plasma cytokines in these associations are limited. In discovery ... -
Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study
(BMJ Publishing Group Ltd., 2015)Objective: To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk ... -
Exposure to Secondhand Smoke and Risk of Tuberculosis: Prospective Cohort Study
(Public Library of Science, 2013)Background: Prospective evidence on the association between secondhand-smoke exposure and tuberculosis is limited. Methods: We included 23,827 never smokers from two rounds (2001 and 2005) of Taiwan National Health Interview ... -
Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study
(BioMed Central, 2015)Background: Short-term particulate air pollution exposure is associated with reduced heart rate variability (HRV), a risk factor for cardiovascular morbidity and mortality, in many studies. Associations with sub-chronic ... -
Exposure to teledermatology and resident preparedness for future practice: results of a national survey
(University of California, Davis, 2016)Teledermatology (TD) is an emerging modality for providing remote dermatologic care with high diagnostic and management 25 concordance compared to face-to-face clinic dermatology. TD training among dermatology residency ... -
Exposure to the Chinese Famine in Early Life and the Risk of Hyperglycemia and Type 2 Diabetes in Adulthood
(American Diabetes Association, 2010)OBJECTIVE: Early developmental adaptations in response to undernutrition may play an essential role in susceptibility to type 2 diabetes, particularly for those experiencing a “mismatched rich nutritional environment” in ... -
Exposure to the Chinese Famine in Early Life and the Risk of Metabolic Syndrome in Adulthood
(American Diabetes Association, 2011)Objective: To examine whether exposure to the Chinese famine during fetal life and early childhood is associated with the risks of metabolic syndrome and whether this association is modified by later life environment. ... -
Exposure to Traffic Pollution and Increased Risk of Rheumatoid Arthritis
(National Institute of Environmental Health Sciences, 2009)Background: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that affects approximately 1% of the adult population, and to date, genetic factors explain < 50% of the risk. Particulate air pollution, ... -
Exposure-Response Estimates for Diesel Engine Exhaust and Lung Cancer Mortality Based on Data from Three Occupational Cohorts
(National Institute of Environmental Health Sciences, 2013)Background: Diesel engine exhaust (DEE) has recently been classified as a known human carcinogen. Objective: We derived a meta-exposure–response curve (ERC) for DEE and lung cancer mortality and estimated lifetime excess ... -
Expression Analysis of Barrett's Esophagus-Associated High-Grade Dysplasia in Laser Capture Microdissected Archival Tissue
(American Association for Cancer Research (AACR), 2008)Purpose: Identifying genes differentially expressed in nondysplastic BE (NDBE) from those expressed in high-grade dysplasia (HGD) should be of value in improving our understanding of this transition and may yield new ... -
Expression Analysis of Macrodactyly Identifies Pleiotrophin Upregulation
(Public Library of Science, 2012)Macrodactyly is a rare family of congenital disorders characterized by the diffuse enlargement of 1 or more digits. Multiple tissue types within the affected digits are involved, but skeletal patterning and gross morphological ...