Browsing Harvard Medical School by Title

Now showing items 7338-7357 of 18428

    • A Geometry-Based Particle Filtering Approach to White Matter Tractography 

      Savadjiev, Peter; Rathi, Yogesh; Malcolm, James G.; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (Springer Science + Business Media, 2010)
      We introduce a fibre tractography framework based on a particle filter which estimates a local geometrical model of the underlying white matter tract, formulated as a `streamline flow' using generalized helicoids. The ...

    • Geospatial mapping of access to timely essential surgery in sub-Saharan Africa 

      Juran, Sabrina; Broer, P. Niclas; Klug, Stefanie J.; Snow, Rachel C.; Okiro, Emelda A.; Ouma, Paul O.; Snow, Robert W.; Tatem, Andrew J.; Meara, John; Alegana, Victor A. (BMJ, 2018-08)

    • Geriatric Syndromes: Clinical, Research, and Policy Implications of a Core Geriatric Concept 

      Inouye, Sharon K.; Studenski, Stephanie; Tinetti, Mary E.; Kuchel, George A. (Wiley-Blackwell, 2007)
      Geriatricians have embraced the term “geriatric syndrome,” using it extensively to highlight the unique features of common health conditions in older people. Geriatric syndromes, such as delirium, falls, incontinence, and ...

    • Germline Progenitors Escape the Widespread Phenomenon of Homolog Pairing during Drosophila Development 

      Joyce, Eric F.; Apostolopoulos, Nicholas; Beliveau, Brian J.; Wu, C. -ting (Public Library of Science, 2013)
      Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can lead to changes in gene expression, chromosome entanglements, and ...

    • Germline Variation in Superoxide Dismutase-2 (SOD2) and Survival Outcomes after Radiation Therapy for Prostate Cancer: Results from a Test and Validation Set Analysis 

      Margalit, Danielle N.; Jordahl, Kristina M.; Werner, Lillian; Wang, Xiaodong; Lee, Mary Gwo-Shu; Penney, Kathryn L.; Batista, Julie L.; Martin, Neil E.; Chan, June M.; Kantoff, Philip W.; Stampfer, Meir J.; Nguyen, Paul L.; Mucci, Lorelei A. (2016)
      Background: Genetic variants in antioxidant pathways may decrease the efficacy of radiation therapy (RT) by suppressing the generation of reactive oxygen species (ROS). We studied the association between single nucleotide ...

    • Gestational carriers: A viable alternative for women with medical contraindications to pregnancy* 

      Anchan, Raymond M.; Missmer, Stacey A.; Correia, Katharine F.; Ginsburg, Elizabeth S. (2013)
      Objective: Compare the efficacy of surrogate or gestational carrier (GC) cycles to that of autologous in vitro fertilization (IVF)/intracytoplasmic sperm injections (ICSI) in patients with gynecologic or medical co-morbidities ...

    • Gestational Exposure to Endocrine-Disrupting Chemicals and Reciprocal Social, Repetitive, and Stereotypic Behaviors in 4- and 5-Year-Old Children: The HOME Study 

      Braun, Joseph M.; Kalkbrenner, Amy E.; Just, Allan C.; Yolton, Kimberly; Calafat, Antonia M.; Sjödin, Andreas; Hauser, Russ; Webster, Glenys M.; Chen, Aimin; Lanphear, Bruce P. (NLM-Export, 2014)
      Background: Endocrine-disrupting chemicals (EDCs) may be involved in the etiology of autism spectrum disorders, but identifying relevant chemicals within mixtures of EDCs is difficult. Objective: Our goal was to identify ...

    • Gestational Trophoblastic Neoplasia in the 1990s 

      Goldstein, Donald Peter (Yale School of Medicine, 1991)
      Major advances have been achieved during the past 40 years in the epidemiology, etiology, pathology, endocrinology, immunology, diagnosis, and treatment of molar pregnancy (MP) and gestational trophoblastic neoplasia (GTN). ...

    • Getting a Head Start: The Importance of Personal Genetics Education in High Schools 

      Kung, Johnny Tsun-Yi; Gelbart, Marnie E. (Yale School of Medicine, 2012)
      With advances in sequencing technology, widespread and affordable genome sequencing will soon be a reality. However, studies suggest that “genetic literacy” of the general public is inadequate to prepare our society for ...

    • Getting Tie(2)d up in angiogenesis 

      Ramsauer, Markus; D'Amore, Patricia Ann (American Society for Clinical Investigation, 2002)
      Angiogenesis, the growth of new vessels from pre-existing blood vessels, requires complex signaling pathways and a high degree of spatial and temporal coordination among various cell types, multiple pro- and anti-angiogenic ...

    • Getting under the Skin: Report from the International Psoriasis Council Workshop on the Role of Stress in Psoriasis 

      Schwartz, Julia; Evers, Andrea W. M.; Bundy, Christine; Kimball, Alexandra B. (Frontiers Media S.A., 2016)
      Psoriasis is a chronic inflammatory skin condition with significant physical and psychosocial comorbidity. A workshop of leading experts in dermatology and psychology with the purpose of better understanding the current ...

    • GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo 

      Bach, Erika A.; Ekas, Laura A.; Ayala-Camargo, Aidee; Flaherty, Maria Sol; Lee, Haeryun; Perrimon, Norbert; Baeg, Gyeong-Hun (Elsevier, 2007)

    • GGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosis 

      Yu, De-cai; Liu, Jia; Chen, Jun; Shao, Jiao-jiao; Shen, Xiao; Xia, Hong-guang; Li, Chao-jun; Xue, Bin; Ding, Yi-tao (BioMed Central, 2014)
      Background: Hepatocellular carcinoma (HCC) has been associated with diabetes and obesity, but a possible connection with the metabolic syndrome (MetS) and its potential interaction with hepatitis and cirrhosis are open to ...

    • Ghana randomized air pollution and health study (GRAPHS): study protocol for a randomized controlled trial 

      Jack, Darby W.; Asante, Kwaku Poku; Wylie, Blair J.; Chillrud, Steve N.; Whyatt, Robin M.; Ae-Ngibise, Kenneth A.; Quinn, Ashlinn K.; Yawson, Abena Konadu; Boamah, Ellen Abrafi; Agyei, Oscar; Mujtaba, Mohammed; Kaali, Seyram; Kinney, Patrick; Owusu-Agyei, Seth (BioMed Central, 2015)
      Background: Household air pollution exposure is a major health risk, but validated interventions remain elusive. Methods/Design The Ghana Randomized Air Pollution and Health Study (GRAPHS) is a cluster-randomized trial ...

    • Ghrelin 

      Müller, T.D.; Nogueiras, R.; Andermann, M.L.; Andrews, Z.B.; Anker, S.D.; Argente, J.; Batterham, R.L.; Benoit, S.C.; Bowers, C.Y.; Broglio, F.; Casanueva, F.F.; D'Alessio, D.; Depoortere, I.; Geliebter, A.; Ghigo, E.; Cole, P.A.; Cowley, M.; Cummings, D.E.; Dagher, A.; Diano, S.; Dickson, S.L.; Diéguez, C.; Granata, R.; Grill, H.J.; Grove, K.; Habegger, K.M.; Heppner, K.; Heiman, M.L.; Holsen, L.; Holst, B.; Inui, A.; Jansson, J.O.; Kirchner, H.; Korbonits, M.; Laferrère, B.; LeRoux, C.W.; Lopez, M.; Morin, S.; Nakazato, M.; Nass, R.; Perez-Tilve, D.; Pfluger, P.T.; Schwartz, T.W.; Seeley, R.J.; Sleeman, M.; Sun, Y.; Sussel, L.; Tong, J.; Thorner, M.O.; van der Lely, A.J.; van der Ploeg, L.H.T.; Zigman, J.M.; Kojima, M.; Kangawa, K.; Smith, R.G.; Horvath, T.; Tschöp, M.H. (Elsevier, 2015)
      Background: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the ...

    • Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a 

      Zaniolo, Karine; Sapieha, Przemyslaw; Shao, Zhuo; Stahl, Andreas; Zhu, Tang; Tremblay, Sophie; Picard, Emilie; Madaan, Ankush; Blais, Martine; Lachapelle, Pierre; Mancini, Joseph; Hardy, Pierre; Smith, Lois Elaine Hodgson; Ong, Huy; Chemtob, Sylvain (Association for Research in Vision and Ophthalmology (ARVO), 2011)
      PURPOSE: Vascular degeneration and the ensuing abnormal vascular proliferation are central to proliferative retinopathies. Given the metabolic discordance associated with these diseases, the authors explored the role of ...

    • Giant Adrenal Myelolipoma Masquerading as Heart Failure 

      Joy, Parijat S.; Marak, Creticus P.; Nashed, Nadia S.; Guddati, Achuta K. (S. Karger AG, 2014)
      Adrenal myelolipomas are rare benign tumors of the adrenal cortex composed of adipose and hematopoietic cells. They have been postulated to arise from repeated stimulation by stress, inflammation and ACTH oversecretion. ...

    • Giant mesenteric lymphatic malformation presenting as small bowel volvulus 

      Cauley, Christy E.; Spencer, Philip J.; Sagar, Pallavi; Goldstein, Allan M. (Oxford University Press, 2013)
      Abdominal pain with bilious emesis is an ominous clinical presentation with many possible causes. We describe a previously healthy 4-year-old boy who presented with these symptoms and ultrasound findings of fluid throughout ...

    • Giant Pyogenic Granuloma in a Patient with Chronic Lymphocytic Leukemia 

      Plovanich, Molly; Tsibris, Hillary C.; Lian, Christine G.; Mostaghimi, Arash (S. Karger AG, 2014)
      Pyogenic granuloma, also known as lobular capillary hemangioma, is a common benign vascular proliferative lesion that can present at any age on the skin or mucous membranes. Most lesions do not exceed 2 cm, but there are ...

    • Gibbon genome and the fast karyotype evolution of small apes 

      Carbone, Lucia; Harris, R. Alan; Gnerre, Sante; Veeramah, Krishna R.; Lorente-Galdos, Belen; Huddleston, John; Meyer, Thomas J.; Herrero, Javier; Roos, Christian; Aken, Bronwen; Anaclerio, Fabio; Archidiacono, Nicoletta; Baker, Carl; Barrell, Daniel; Batzer, Mark A.; Beal, Kathryn; Blancher, Antoine; Bohrson, Craig L.; Brameier, Markus; Campbell, Michael S.; Capozzi, Oronzo; Casola, Claudio; Chiatante, Giorgia; Cree, Andrew; Damert, Annette; de Jong, Pieter J.; Dumas, Laura; Fernandez-Callejo, Marcos; Flicek, Paul; Fuchs, Nina V.; Gut, Marta; Gut, Ivo; Hahn, Matthew W.; Hernandez-Rodriguez, Jessica; Hillier, LaDeana W.; Hubley, Robert; Ianc, Bianca; Izsvák, Zsuzsanna; Jablonski, Nina G.; Johnstone, Laurel M.; Karimpour-Fard, Anis; Konkel, Miriam K.; Kostka, Dennis; Lazar, Nathan H.; Lee, Sandra L.; Lewis, Lora R.; Liu, Yue; Locke, Devin P.; Mallick, Swapan; Mendez, Fernando L.; Muffato, Matthieu; Nazareth, Lynne V.; Nevonen, Kimberly A.; O,Bleness, Majesta; Ochis, Cornelia; Odom, Duncan T.; Pollard, Katherine S.; Quilez, Javier; Reich, David; Rocchi, Mariano; Schumann, Gerald G.; Searle, Stephen; Sikela, James M.; Skollar, Gabriella; Smit, Arian; Sonmez, Kemal; Hallers, Boudewijn ten; Terhune, Elizabeth; Thomas, Gregg W.C.; Ullmer, Brygg; Ventura, Mario; Walker, Jerilyn A.; Wall, Jeffrey D.; Walter, Lutz; Ward, Michelle C.; Wheelan, Sarah J.; Whelan, Christopher W.; White, Simon; Wilhelm, Larry J.; Woerner, August E.; Yandell, Mark; Zhu, Baoli; Hammer, Michael F.; Marques-Bonet, Tomas; Eichler, Evan E.; Fulton, Lucinda; Fronick, Catrina; Muzny, Donna M.; Warren, Wesley C.; Worley, Kim C.; Rogers, Jeffrey; Wilson, Richard K.; Gibbs, Richard A. (2014)
      Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal rearrangement and occupy a key node in the primate phylogeny between Old World monkeys and great apes. Here we present the assembly ...