Browsing Harvard Medical School by Title
Now showing items 7610-7629 of 18427
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Heart Block and Nonocclusive Mesenteric Ischemia
(Springer-Verlag, 2009) -
Heart Failure in Patients With Stable Atherosclerosis: A Post Hoc Analysis of the TRA 2°P-TIMI 50 Trial
(2018-05-15)Background: Heart failure is a growing public health burden and a morbid complication of atherosclerotic cardiovascular disease. Antiplatelet therapy is commonly used for the secondary prevention of atherothrombotic ... -
Heart field origin of great vessel precursors relies on nkx2.5-mediated vasculogenesis
(2013)The pharyngeal arch arteries (PAAs) are transient embryonic blood vessels that make indispensable contributions to the carotid arteries and great vessels of the heart, including the aorta and pulmonary artery1, 2. During ... -
Heart of Darkness: The Downside of Trastuzumab
(American Society of Clinical Oncology (ASCO), 2006)Trastuzumab has been shown to be quite effective in reducing suffering and mortality from breast cancer in both the metastatic and adjuvant settings. With short follow-up, remarkably consistent results across five adjuvant, ... -
Heart on a Plate: Histological and Functional Assessment of Isolated Adult Zebrafish Hearts Maintained in Culture
(Public Library of Science, 2014)The zebrafish is increasingly used for cardiovascular genetic and functional studies. We present a novel protocol to maintain and monitor whole isolated beating adult zebrafish hearts in culture for long-term experiments. ... -
Heart Rate at Hospital Discharge in Patients With Heart Failure Is Associated With Mortality and Rehospitalization
(Blackwell Publishing Ltd, 2015)Background: Whether heart rate upon discharge following hospitalization for heart failure is associated with long‐term adverse outcomes and whether this association differs between patients with sinus rhythm (SR) and atrial ... -
Heart Rate Dynamics after Combined Strength and Endurance Training in Middle-Aged Women: Heterogeneity of Responses
(Public Library of Science, 2013)The loss of complexity in physiological systems may be a dynamical biomarker of aging and disease. In this study the effects of combined strength and endurance training compared with those of endurance training or strength ... -
Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study
(BioMed Central, 2014)Background: In occupational settings, boilermakers are exposed to high levels of metallic fine particulate matter (PM2.5) generated during the welding process. The effect of welding PM2.5 on heart rate variability (HRV) ... -
Heart Rate Variability and Its Role in Predicting Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Graft
(Informa UK Limited, 2023-10)Background: An association between heart rate variability (HRV) and cardiac events in certain diseases has been demonstrated. However, the association with new-onset atrial fibrillation (AF) after coronary artery bypass ... -
Heart rate variability biofeedback in patients with alcohol dependence: a randomized controlled study
(Dove Medical Press, 2015)Background and objective In patients with alcohol dependence, ethyl-toxic damage of vasomotor and cardiac autonomic nerve fibers leads to autonomic imbalance with neurovascular and cardiac dysfunction, the latter resulting ... -
Heart rhythm complexity impairment in patients undergoing peritoneal dialysis
(Nature Publishing Group, 2016)Cardiovascular disease is one of the leading causes of death in patients with advanced renal disease. The objective of this study was to investigate impairments in heart rhythm complexity in patients with end-stage renal ... -
Heart Valve Tissue Engineering: Concepts, Approaches, Progress, and Challenges
(Kluwer Academic Publishers-Plenum Publishers, 2006)Potential applications of tissue engineering in regenerative medicine range from structural tissues to organs with complex function. This review focuses on the engineering of heart valve tissue, a goal which involves a ... -
Heartbeat Perception in Panic Disorder: a Reanalysis
(2000)This article describes a reanalysis of seven studies on heart beat perception (HBP) in panic disorder. The pooled sample had 709 participants from eight diagnostic categories. Accurate HBP was uncommon, but more prevalent ... -
Hearty miR-363 controls HAND1 in cardiac cell specification
(BioMed Central, 2014)MicroRNAs regulate target gene expression post-transcriptionally in a myriad of cell types and play critical roles in diverse physiological and pathological processes, including cardiomyocyte development, differentiation, ... -
Heat Shock Protein-90 Inhibitors Enhance Antigen Expression on Melanomas and Increase T Cell Recognition of Tumor Cells
(Public Library of Science, 2014)In an effort to enhance antigen-specific T cell recognition of cancer cells, we have examined numerous modulators of antigen-expression. In this report we demonstrate that twelve different Hsp90 inhibitors (iHsp90) share ... -
Heat Shock Proteins, Autoimmunity, and Cancer Treatment
(Hindawi Publishing Corporation, 2012)Heat shock proteins (HSPs) have been linked to the therapy of both cancer and inflammatory diseases, approaches that utilize contrasting immune properties of these proteins. It would appear that HSP family members Hsp60 ... -
Heat Shock Proteins: Conditional Mediators of Inflammation in Tumor Immunity
(Frontiers Research Foundation, 2012)Heat shock protein (HSP)-based anticancer vaccines have undergone successful preclinical testing and are now entering clinical trial. Questions still remain, however regarding the immunological properties of HSPs. It is ... -
Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish
(National Academy of Sciences, 2007)RAS family members are among the most frequently mutated oncogenes in human cancers. Given the utility of zebrafish in both chemical and genetic screens, developing RAS-induced cancer models will make large-scale screens ... -
Heat stress-induced memory impairment is associated with neuroinflammation in mice
(BioMed Central, 2015)Background: Heat stress induces many pathophysiological responses and has a profound impact on brain structure. It has been demonstrated that exposure to high temperature induces cognitive impairment in experimental animals ...