Browsing Harvard Medical School by Keyword "Acute Liver Failure"

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    • Mechanisms of Xenogeneic Baboon Platelet Aggregation and Phagocytosis by Porcine Liver Sinusoidal Endothelial Cells 

      Peng, Qiang; Yeh, Heidi; Wei, Lingling; Enjyoj, Keiichi; Machaidze, Zurab; Csizmad, Eva; Schuetz, Christian; Lee, Kang Mi; Deng, Shaoping; Robson, Simon Christopher; Markmann, James; Buhler, Leo (Public Library of Science, 2012)
      Background: Baboons receiving xenogeneic livers from wild type and transgenic pigs survive less than 10 days. One of the major issues is the early development of profound thrombocytopenia that results in fatal hemorrhage. ...

    • The Uncoordinated-5 Homolog B Receptor Affects Hepatic Ischemia Reperfusion Injury 

      König, Klemens; Köhler, David; Granja, Tiago; Jennewein, Carla; Tran, Nguyen; Mirakaj, Valbona; Kröhnert, Friedemann; Rosenberger, Peter (Public Library of Science, 2012)
      Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver ...