Browsing Harvard Medical School by Keyword "Arachidonic Acid Signaling Cascades"

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    • Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice 

      He, Chengwei; Qu, Xiying; Wan, Jianbo; Rong, Rong; Huang, Lili; Cai, Chun; Zhou, Keyuan; Gu, Yan; Qian, Steven Y.; Kang, Jing Xuan (Public Library of Science, 2012)
      Recent studies have shown that a tumor-supportive microenvironment is characterized by high levels of pro-inflammatory and pro-angiogenic eicosanoids derived from omega-6 (n−6) arachidonic acid (AA). Although the metabolic ...