Browsing Harvard Medical School by Keyword "Autoimmune diseases"

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    • The Dichotomous Pattern of IL-12R and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation 

      Chognard, Gaëlle; Bellemare, Lisa; Pelletier, Adam-Nicolas; Dominguez-Punaro, Maria C.; Beauchamp, Claudine; Guyon, Marie-Josée; Charron, Guy; Morin, Nicolas; Sivanesan, Durga; Kuchroo, Vijay; Xavier, Ramnik; Michnick, Stephen W.; Chemtob, Sylvain; Rioux, John D.; Lesage, Sylvie (Public Library of Science, 2014)
      IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23 receptors share a common subunit, it has been assumed that ...