Browsing Harvard Medical School by Keyword "BHD"
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Folliculin regulates cell–cell adhesion, AMPK, and mTORC1 in a cell‐type‐specific manner in lung‐derived cells
(Wiley Periodicals, Inc., 2014)Abstract Germline loss‐of‐function BHD mutations cause cystic lung disease and hereditary pneumothorax, yet little is known about the impact of BHD mutations in the lung. Folliculin (FLCN), the product of the Birt–Hogg–Dube ... -
Loss of the Birt–Hogg–Dube Tumor Suppressor Results in Apoptotic Resistance due to Aberrant TGFb-Mediated Transcription
(Nature Publishing Group, 2011)Birt–Hogg–Dubé (BHD) syndrome is an inherited cancer susceptibility disease characterized by skin and kidney tumors, as well as cystic lung disease, which results from loss-of-function mutations in the BHD gene. BHD is ...